Bioavailability of Potassium From Potatoes and Potassium Gluconate
| Status: | Completed |
|---|---|
| Conditions: | High Blood Pressure (Hypertension) |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 20 - 60 |
| Updated: | 5/11/2018 |
| Start Date: | March 1, 2013 |
| End Date: | December 2014 |
This study is designed to compare the effect of sources of potassium on uptake and the effect
of potassium on blood pressure.
of potassium on blood pressure.
The study will compare uptake of potassium from three different doses and sources;
supplements (720, 1440 and 2160 mg) potatoes (720, 1440 and 2160 mg) or French fries (2160
mg).
During 9 phases, participants will consume a controlled diet with the supplements, potato or
french fries (every other week for 5 days). On the 4th day, blood and urine samples will be
taken to monitor potassium uptake and excretion. Measures of blood pressure will be analyzed
at defined time points throughout the intervention.
supplements (720, 1440 and 2160 mg) potatoes (720, 1440 and 2160 mg) or French fries (2160
mg).
During 9 phases, participants will consume a controlled diet with the supplements, potato or
french fries (every other week for 5 days). On the 4th day, blood and urine samples will be
taken to monitor potassium uptake and excretion. Measures of blood pressure will be analyzed
at defined time points throughout the intervention.
Inclusion Criteria:
- Able to adhere to the visit schedule, protocol requirements and available to complete
the study
- Normotensive men and women
- Aged 20-60 years
- BMI of 15-35
Exclusion Criteria:
- Medication to treat hypertension or hypotension
- Medication known to affect electrolyte metabolism or contain high levels of potassium
or sodium
- smoke cigarettes or use illegal drugs
- Hypertension or hypotension
- Diseases known to affect potassium metabolism
- Pregnant
- Allergic to nuts
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