An Extension Study in Participants With Moderate to Severe Rheumatoid Arthritis



Status:Active, not recruiting
Conditions:Arthritis, Rheumatoid Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - Any
Updated:12/6/2018
Start Date:June 27, 2013
End Date:March 22, 2024

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A Phase 3, Multicenter Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Patients With Rheumatoid Arthritis

The purpose of this study is to investigate the long-term safety and any side effects of
baricitinib in participants who have completed a previous baricitinib rheumatoid arthritis
study.

The study provides for 7 years of additional treatment with baricitinib.


Inclusion Criteria:

- Have completed the final active treatment in study JADV (NCT01710358), JADZ
(NCT01711359), JADX (NCT01721057), JADW (NCT01721044), JADA (NCT01185353) or JAGS
(planned start date in August 2014)

Exclusion Criteria:

- Have significant uncontrolled cerebro-cardiovascular (eg, myocardial infarction [MI],
unstable angina, unstable arterial hypertension, severe heart failure, or
cerebrovascular accident), respiratory, hepatic, renal, gastrointestinal, endocrine,
hematologic, neuropsychiatric disorders, or abnormal laboratory values that developed
during a previous baricitinib study that, in the opinion of the investigator, pose an
unacceptable risk to the participant if investigational product continues to be
administered

- Have a known hypersensitivity to baricitinib or any component of this investigational
product

- Had investigational product permanently discontinued at any time during a previous
baricitinib study

- Had temporary investigational product interruption at the final study visit of a
previous baricitinib study and, in the opinion of the investigator, this poses an
unacceptable risk for participation in the study

- Have any other condition that, in the opinion of the investigator, renders the
participant unable to understand the nature, scope, and possible consequences of the
study or precludes the participant from following and completing the protocol
We found this trial at
68
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1654
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Mesa, AZ
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1044 SW 44th Street
Oklahoma City, Oklahoma 73109
405-616-4888
851
mi
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Oklahoma City, OK
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
2026
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Portland, OR
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Albany, New York 12206
514
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Albany, NY
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Albuquerque, New Mexico
1333
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Albuquerque, NM
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302
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Asheville, NC
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?
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Bahía Blanca,
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Bethlehem, Pennsylvania 18017
234
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Bethlehem, PA
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Boise, Idaho 83702
1716
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Boise, ID
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Boulder, Colorado 80304
1174
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Boulder, CO
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Boynton Beach, Florida 33472
943
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Boynton Beach, FL
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350
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Charlotte, NC
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Chesapeake, Virginia 23320
430
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Chesapeake, VA
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Columbia, Missouri 65211
(573) 882-2121
University of Missouri T he University of Missouri was founded in 1839 in Columbia, Mo.,...
501
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Columbia, MO
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Cumberland, Maryland 21502
226
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Cumberland, MD
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Cypress, Texas 77429
830
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Cypress, TX
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905
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Dallas, TX
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Danbury, Connecticut 06810
510
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Danbury, CT
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Denver, Colorado 80230
1157
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Denver, CO
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Duncansville, Pennsylvania 16635
244
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Duncansville, PA
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660
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Flowood, MS
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Franklin, Wisconsin 53132
328
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Franklin, WI
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Freehold, New Jersey 07728
461
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Freehold, NJ
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Fresno, California 93720
1986
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Fresno, CA
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1663
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Glendale, AZ
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Grand Rapids, Michigan 49546
241
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Grand Rapids, MI
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Hartsdale, New York 10530
489
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Hartsdale, NY
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Indianapolis, Indiana 46202
166
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Indianapolis, IN
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Indianapolis, Indiana 46227
166
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Indianapolis, IN
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Indianapolis, Indiana 46260
167
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Indianapolis, IN
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Kalamazoo, Michigan 49009
211
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Kalamazoo, MI
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Kennewick, Washington 99336
1856
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Kennewick, WA
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La Jolla, California 92037
1954
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La Jolla, CA
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Lansing, Michigan 48910
203
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Lansing, MI
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Lansing, Michigan 48910
207
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Lansing, MI
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Las Vegas, Nevada 89128
1756
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Las Vegas, NV
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Lewes, Delaware 19958
428
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Lewes, DE
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1134
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Lubbock, TX
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Middleburg Heights, Ohio 44130
115
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Middleburg Heights, OH
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Myrtle Beach, South Carolina 29572
490
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Myrtle Beach, SC
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Naples, Florida 34102
957
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Naples, FL
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Nassau Bay, Texas 77058
991
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Nassau Bay, TX
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New Port Richey, Florida 34652
809
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New Port Richey, FL
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Orlando, Florida 32804
792
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Orlando, FL
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796
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Orlando, FL
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Palm Desert, California 92260
1882
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Palm Desert, CA
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Palm Harbor, Florida 34684
821
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Palo Alto, California 94305
2099
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Palo Alto, CA
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Peoria, Arizona 85381
1667
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Peoria, AZ
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Philadelphia, Pennsylvania 19152
416
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Philadelphia, PA
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Phoenix, Arizona 85023
1662
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Phoenix, AZ
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356
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Rochester, NY
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Saint Louis, Missouri 63117
401
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Saint Louis, MO
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Saint Louis, Missouri 63141
408
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Saint Louis, MO
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Santa Maria, California 93454
1987
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Santa Maria, CA
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Seattle, Washington 98133
2007
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Seattle, WA
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963
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Tamarac, FL
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Tampa, Florida 33613
821
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Tampa, FL
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Tampa, Florida 33614
826
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Tampa, FL
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Toms River, New Jersey 08755
467
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Toms River, NJ
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Trumbull, Connecticut 06611
521
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Trumbull, CT
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Tucson, Arizona 85721
(520) 621-2211
University of Arizona The University of Arizona is a premier, public research university. Established in...
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Tulsa, Oklahoma 74135
750
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Tulsa, OK
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Upland, California 91786
1940
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Upland, CA
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Vancouver, Washington 98664
2021
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Vancouver, WA
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Vernon Hills, Illinois 60061
301
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Vernon Hills, IL
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Webster, Texas 77508
987
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Webster, TX
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Wyomissing, Pennsylvania 19610
373
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Wyomissing, PA
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