An Extension Study in Participants With Moderate to Severe Rheumatoid Arthritis



Status:Active, not recruiting
Conditions:Arthritis, Rheumatoid Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - Any
Updated:12/6/2018
Start Date:June 27, 2013
End Date:March 22, 2024

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A Phase 3, Multicenter Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Patients With Rheumatoid Arthritis

The purpose of this study is to investigate the long-term safety and any side effects of
baricitinib in participants who have completed a previous baricitinib rheumatoid arthritis
study.

The study provides for 7 years of additional treatment with baricitinib.


Inclusion Criteria:

- Have completed the final active treatment in study JADV (NCT01710358), JADZ
(NCT01711359), JADX (NCT01721057), JADW (NCT01721044), JADA (NCT01185353) or JAGS
(planned start date in August 2014)

Exclusion Criteria:

- Have significant uncontrolled cerebro-cardiovascular (eg, myocardial infarction [MI],
unstable angina, unstable arterial hypertension, severe heart failure, or
cerebrovascular accident), respiratory, hepatic, renal, gastrointestinal, endocrine,
hematologic, neuropsychiatric disorders, or abnormal laboratory values that developed
during a previous baricitinib study that, in the opinion of the investigator, pose an
unacceptable risk to the participant if investigational product continues to be
administered

- Have a known hypersensitivity to baricitinib or any component of this investigational
product

- Had investigational product permanently discontinued at any time during a previous
baricitinib study

- Had temporary investigational product interruption at the final study visit of a
previous baricitinib study and, in the opinion of the investigator, this poses an
unacceptable risk for participation in the study

- Have any other condition that, in the opinion of the investigator, renders the
participant unable to understand the nature, scope, and possible consequences of the
study or precludes the participant from following and completing the protocol
We found this trial at
68
sites
1440
mi
from 98109
Lubbock, TX
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1044 SW 44th Street
Oklahoma City, Oklahoma 73109
405-616-4888
1525
mi
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Oklahoma City, OK
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
147
mi
from 98109
Portland, OR
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Albany, New York 12206
2351
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Albany, NY
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Albuquerque, New Mexico
1184
mi
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Albuquerque, NM
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2187
mi
from 98109
Asheville, NC
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?
mi
from 98109
Bahía Blanca,
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Bethlehem, Pennsylvania 18017
2178
mi
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Bethlehem, PA
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Boise, Idaho 83702
406
mi
from 98109
Boise, ID
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Boulder, Colorado 80304
995
mi
from 98109
Boulder, CO
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Boynton Beach, Florida 33472
2701
mi
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Boynton Beach, FL
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2283
mi
from 98109
Charlotte, NC
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Chesapeake, Virginia 23320
2437
mi
from 98109
Chesapeake, VA
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Columbia, Missouri 65211
(573) 882-2121
University of Missouri T he University of Missouri was founded in 1839 in Columbia, Mo.,...
1612
mi
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Columbia, MO
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Cumberland, Maryland 21502
2215
mi
from 98109
Cumberland, MD
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Cypress, Texas 77429
1731
mi
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Cypress, TX
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1677
mi
from 98109
Dallas, TX
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Danbury, Connecticut 06810
2406
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Danbury, CT
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Denver, Colorado 80230
1025
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Denver, CO
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Duncansville, Pennsylvania 16635
2206
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Duncansville, PA
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1985
mi
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Flowood, MS
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Franklin, Wisconsin 53132
1685
mi
from 98109
Franklin, WI
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Freehold, New Jersey 07728
2404
mi
from 98109
Freehold, NJ
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Fresno, California 93720
755
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Fresno, CA
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1104
mi
from 98109
Glendale, AZ
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Grand Rapids, Michigan 49546
1802
mi
from 98109
Grand Rapids, MI
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Hartsdale, New York 10530
2402
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Hartsdale, NY
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Indianapolis, Indiana 46202
1868
mi
from 98109
Indianapolis, IN
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Indianapolis, Indiana 46227
1868
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Indianapolis, IN
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Indianapolis, Indiana 46260
1862
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Indianapolis, IN
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Kalamazoo, Michigan 49009
1812
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Kalamazoo, MI
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Kennewick, Washington 99336
179
mi
from 98109
Kennewick, WA
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La Jolla, California 92037
1056
mi
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La Jolla, CA
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Lansing, Michigan 48910
1855
mi
from 98109
Lansing, MI
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Lansing, Michigan 48910
1851
mi
from 98109
Lansing, MI
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Las Vegas, Nevada 89128
873
mi
from 98109
Las Vegas, NV
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Lewes, Delaware 19958
2414
mi
from 98109
Lewes, DE
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1125
mi
from 98109
Mesa, AZ
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Middleburg Heights, Ohio 44130
2019
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Middleburg Heights, OH
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Myrtle Beach, South Carolina 29572
2434
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Myrtle Beach, SC
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Naples, Florida 34102
2643
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Naples, FL
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Nassau Bay, Texas 77058
1912
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Nassau Bay, TX
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New Port Richey, Florida 34652
2501
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New Port Richey, FL
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Orlando, Florida 32804
2544
mi
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Orlando, FL
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2549
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Orlando, FL
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Palm Desert, California 92260
1010
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Palm Desert, CA
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Palm Harbor, Florida 34684
2508
mi
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Palm Harbor, FL
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Palo Alto, California 94305
704
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Palo Alto, CA
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Peoria, Arizona 85381
1104
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Peoria, AZ
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Philadelphia, Pennsylvania 19152
2373
mi
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Philadelphia, PA
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Phoenix, Arizona 85023
1116
mi
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Phoenix, AZ
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2165
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Rochester, NY
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Saint Louis, Missouri 63117
1714
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Saint Louis, MO
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Saint Louis, Missouri 63141
1706
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Saint Louis, MO
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Santa Maria, California 93454
953
mi
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Santa Maria, CA
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Seattle, Washington 98133
7
mi
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Seattle, WA
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2708
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Tamarac, FL
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Tampa, Florida 33613
2519
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Tampa, FL
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Tampa, Florida 33614
2522
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Tampa, FL
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Toms River, New Jersey 08755
2418
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Toms River, NJ
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Trumbull, Connecticut 06611
2421
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Trumbull, CT
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Tucson, Arizona 85721
(520) 621-2211
University of Arizona The University of Arizona is a premier, public research university. Established in...
1220
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Tucson, AZ
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Tulsa, Oklahoma 74135
1564
mi
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Tulsa, OK
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Upland, California 91786
965
mi
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Upland, CA
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Vancouver, Washington 98664
139
mi
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Vancouver, WA
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Vernon Hills, Illinois 60061
1707
mi
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Vernon Hills, IL
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Webster, Texas 77508
1904
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Webster, TX
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Wyomissing, Pennsylvania 19610
2323
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Wyomissing, PA
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