An Extension Study in Participants With Moderate to Severe Rheumatoid Arthritis



Status:Active, not recruiting
Conditions:Arthritis, Rheumatoid Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - Any
Updated:12/6/2018
Start Date:June 27, 2013
End Date:March 22, 2024

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A Phase 3, Multicenter Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Patients With Rheumatoid Arthritis

The purpose of this study is to investigate the long-term safety and any side effects of
baricitinib in participants who have completed a previous baricitinib rheumatoid arthritis
study.

The study provides for 7 years of additional treatment with baricitinib.


Inclusion Criteria:

- Have completed the final active treatment in study JADV (NCT01710358), JADZ
(NCT01711359), JADX (NCT01721057), JADW (NCT01721044), JADA (NCT01185353) or JAGS
(planned start date in August 2014)

Exclusion Criteria:

- Have significant uncontrolled cerebro-cardiovascular (eg, myocardial infarction [MI],
unstable angina, unstable arterial hypertension, severe heart failure, or
cerebrovascular accident), respiratory, hepatic, renal, gastrointestinal, endocrine,
hematologic, neuropsychiatric disorders, or abnormal laboratory values that developed
during a previous baricitinib study that, in the opinion of the investigator, pose an
unacceptable risk to the participant if investigational product continues to be
administered

- Have a known hypersensitivity to baricitinib or any component of this investigational
product

- Had investigational product permanently discontinued at any time during a previous
baricitinib study

- Had temporary investigational product interruption at the final study visit of a
previous baricitinib study and, in the opinion of the investigator, this poses an
unacceptable risk for participation in the study

- Have any other condition that, in the opinion of the investigator, renders the
participant unable to understand the nature, scope, and possible consequences of the
study or precludes the participant from following and completing the protocol
We found this trial at
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Indianapolis, Indiana 46227
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1044 SW 44th Street
Oklahoma City, Oklahoma 73109
405-616-4888
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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Albany, New York 12206
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Albuquerque, New Mexico
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Bethlehem, Pennsylvania 18017
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Boise, Idaho 83702
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Boulder, Colorado 80304
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Boynton Beach, Florida 33472
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Charlotte, NC
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Chesapeake, Virginia 23320
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Columbia, Missouri 65211
(573) 882-2121
University of Missouri T he University of Missouri was founded in 1839 in Columbia, Mo.,...
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Cumberland, Maryland 21502
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Cypress, Texas 77429
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Danbury, Connecticut 06810
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Denver, Colorado 80230
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Duncansville, Pennsylvania 16635
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Flowood, MS
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Franklin, Wisconsin 53132
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Freehold, New Jersey 07728
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Fresno, California 93720
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Glendale, AZ
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Grand Rapids, Michigan 49546
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Hartsdale, New York 10530
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Indianapolis, Indiana 46202
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Indianapolis, Indiana 46260
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Kalamazoo, Michigan 49009
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Kennewick, Washington 99336
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La Jolla, California 92037
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Lansing, Michigan 48910
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Lansing, Michigan 48910
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Las Vegas, Nevada 89128
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Lewes, Delaware 19958
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Mesa, AZ
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Middleburg Heights, Ohio 44130
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Myrtle Beach, South Carolina 29572
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Naples, Florida 34102
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Nassau Bay, Texas 77058
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New Port Richey, Florida 34652
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Orlando, Florida 32804
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Palm Desert, California 92260
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Palm Harbor, Florida 34684
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Palo Alto, California 94305
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Peoria, Arizona 85381
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Philadelphia, Pennsylvania 19152
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Phoenix, Arizona 85023
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Saint Louis, Missouri 63117
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Saint Louis, Missouri 63141
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Santa Maria, California 93454
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Seattle, Washington 98133
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Tampa, Florida 33613
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Tampa, Florida 33614
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Toms River, New Jersey 08755
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Trumbull, Connecticut 06611
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Tucson, Arizona 85721
(520) 621-2211
University of Arizona The University of Arizona is a premier, public research university. Established in...
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Tulsa, Oklahoma 74135
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Upland, California 91786
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Vancouver, Washington 98664
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Vernon Hills, Illinois 60061
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Webster, Texas 77508
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Wyomissing, Pennsylvania 19610
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