Retaining Cognition While Avoiding Late-Life Depression
| Status: | Completed |
|---|---|
| Conditions: | Cognitive Studies, Depression |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 60 - Any |
| Updated: | 11/19/2017 |
| Start Date: | July 2011 |
| End Date: | July 2016 |
RECALL: Retaining Cognition While Avoiding Late-Life Depression
This study will adapt Problem Solving Therapy (PST) for individuals with mild cognitive
impairment (MCI) as an intervention for preventing major depression (DEP). PST will be
modified so as to be provided to both MCI probands as well as their support person. The
primary aim is to examine the effectiveness of PST in individuals with MCI and the support
person, at preventing DEP over 12 mos. in MCI probands. We also will examine the effect of
exercise on preventing depression.
impairment (MCI) as an intervention for preventing major depression (DEP). PST will be
modified so as to be provided to both MCI probands as well as their support person. The
primary aim is to examine the effectiveness of PST in individuals with MCI and the support
person, at preventing DEP over 12 mos. in MCI probands. We also will examine the effect of
exercise on preventing depression.
The Recall Study (Retaining Cognition while Avoiding Late-Life Depression) is a study for
adults 60 and older who have noticed mild memory changes in themselves or a loved one. Mild
memory changes may feel stressful and therefore increase an individual's risk of developing
depression. This research project will test whether Problem Solving Therapy (PST) is
successful in preventing major depression for those living with mild cognitive impairments.
We will also examine the effect of modest exercise on mood. You will participate in 8 to 12
PST sessions over 16 weeks. All treatments are provided at no cost and there is compensation
for participation.
adults 60 and older who have noticed mild memory changes in themselves or a loved one. Mild
memory changes may feel stressful and therefore increase an individual's risk of developing
depression. This research project will test whether Problem Solving Therapy (PST) is
successful in preventing major depression for those living with mild cognitive impairments.
We will also examine the effect of modest exercise on mood. You will participate in 8 to 12
PST sessions over 16 weeks. All treatments are provided at no cost and there is compensation
for participation.
MCI participant Inclusion Criteria:
1. => age 60
2. Modified Mini Mental State (3MS) => 80
3. MCI diagnosis
4. Adequate physical and sensory function to undergo NP assessment
5. PHQ-9 score 1-9, with at least one of the cardinal symptoms of depression (low mood or
anhedonia) endorsed.
MCI participant Exclusion Criteria:
1. Major Depressive Episode or anxiety disorder within the past 1 year
2. Currently taking an anti-depressant
3. History of Bipolar Disorder or Schizophrenia
4. Drug or alcohol use disorder within 12 months
5. Currently taking anti-anxiety med >4x/week for the past 4 weeks
Support person Inclusion Criteria:
1. => age 18
2. Modified Mini Mental State (3MS) => 80
3. Normal Cognitive Function
4. Adequate physical and sensory function to undergo NP assessment
5. PHQ-9 score 1-9, with at least one of the cardinal symptoms of depression (low mood or
anhedonia) endorsed.
Support person Exclusion Criteria:
1. Major Depressive Episode or anxiety disorder within the past 1 year
2. Currently taking an anti-depressant
3. History of Bipolar Disorder or Schizophrenia
4. Drug or alcohol use disorder within 12 months
5. Currently taking anti-anxiety med >4x/week for the past 4 weeks
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