Using Near-infrared Spectroscopy (NIRS) Monitor to Noninvasively Evaluate Hepatic Venous Saturation
| Status: | Completed |
|---|---|
| Conditions: | Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | Any - 18 |
| Updated: | 7/11/2015 |
| Start Date: | June 2013 |
| End Date: | June 2014 |
| Contact: | Rohit Rao, MD |
| Email: | rrao@phoenixchildrens.com |
| Phone: | 2623094874 |
Clinical studies are required to validate the hepatic NIRS monitor with other regional and
global hemodynamic parameters and to evaluate its clinical use for continuous non-invasive
hemodynamic monitoring. Using newer NIRS sensors the correlation between hepatic regional
oxygen saturation and hepatic venous oxygen saturation (SvHO2) needs to be determined. If
found to correlate then the NIRS can be used to evaluate early liver transplant failure
and/or hepatic artery thrombosis, used as an early marker for shock, and necrotizing
enterocolitis, and finally used in the outpatient setting to evaluate patients with chronic
liver pathologies. If our validation study finds that NIRS monitors are an appropriate
marker of hepatic venous saturation then it will lead to further clinical studies.
global hemodynamic parameters and to evaluate its clinical use for continuous non-invasive
hemodynamic monitoring. Using newer NIRS sensors the correlation between hepatic regional
oxygen saturation and hepatic venous oxygen saturation (SvHO2) needs to be determined. If
found to correlate then the NIRS can be used to evaluate early liver transplant failure
and/or hepatic artery thrombosis, used as an early marker for shock, and necrotizing
enterocolitis, and finally used in the outpatient setting to evaluate patients with chronic
liver pathologies. If our validation study finds that NIRS monitors are an appropriate
marker of hepatic venous saturation then it will lead to further clinical studies.
Inclusion Criteria:
- All pediatric patients (0-18yrs) undergoing cardiac catheterization by the
participating interventional cardiologist at Phoenix Children's Hospital will be
recruited for this investigation
Exclusion Criteria:
- emergency catheterizations,
- procedures in hemodynamically unstable patients,
- patients with repeat catheterizations that have already enrolled in the study
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