Comparing the Adenoma Detection Rate With Air Insufflation, Water Immersion and Water Exchange
| Status: | Completed |
|---|---|
| Conditions: | Lymphoma |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 20 - 80 |
| Updated: | 6/29/2016 |
| Start Date: | May 2013 |
| End Date: | December 2015 |
A Randomized, Controlled Trial Comparing the Adenoma Detection Rate With Air Insufflation, Water Immersion and Water Exchange During Colonoscopy
Interval (missed) cancers and lower than expected mortality reduction of proximal colon
cancers in the United States and elsewhere after screening colonoscopy drew attention to
quality indicators. Missed adenomas which are more likely to be in the proximal colon may be
contributing factors. An independent predictor of the risk of interval cancers is adenoma
detection rate. In pilot observations, the investigators showed that water exchange enhanced
adenoma detection in the right colon (cecum to hepatic flexure). This prospective,
randomized controlled trial will compare water exchange with water immersion and traditional
air insufflation in patients undergoing colonoscopy. The investigators test the hypothesis
that compared with air insufflation and water immersion, water exchange produces a
significantly higher adenoma detection rate in the right colon.
cancers in the United States and elsewhere after screening colonoscopy drew attention to
quality indicators. Missed adenomas which are more likely to be in the proximal colon may be
contributing factors. An independent predictor of the risk of interval cancers is adenoma
detection rate. In pilot observations, the investigators showed that water exchange enhanced
adenoma detection in the right colon (cecum to hepatic flexure). This prospective,
randomized controlled trial will compare water exchange with water immersion and traditional
air insufflation in patients undergoing colonoscopy. The investigators test the hypothesis
that compared with air insufflation and water immersion, water exchange produces a
significantly higher adenoma detection rate in the right colon.
All of the procedures will be recorded and stored as digital files.
Inclusion Criteria:
- Patients undergoing colonoscopy performed by the participating endoscopists
Exclusion Criteria:
- obstructive lesions of the colon known before colonoscopy
- massive ascites
- past history of partial colectomy
- refusal to provide written informed consent
We found this trial at
2
sites
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North Hills, California 91343
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