A Study of Evacetrapib and Digoxin in Healthy Participants
| Status: | Completed |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 10/10/2018 |
| Start Date: | July 2013 |
| End Date: | September 2013 |
Effect of Evacetrapib on the Pharmacokinetics of Digoxin in Healthy Subjects
The main purpose of this study is to determine how much digoxin gets into the blood stream
and how long it takes the body to get rid of it when given with the study drug evacetrapib.
This study will also look at the effect of evacetrapib on the removal of digoxin from the
body by the kidneys. Information about any side effects that may occur will be collected.
This study will last approximately 33 days for each participant, not including screening.
and how long it takes the body to get rid of it when given with the study drug evacetrapib.
This study will also look at the effect of evacetrapib on the removal of digoxin from the
body by the kidneys. Information about any side effects that may occur will be collected.
This study will last approximately 33 days for each participant, not including screening.
Inclusion Criteria:
- Overtly healthy males and females (of non-childbearing potential)
- Have a body mass index of 18 to 32 kilograms per square meter (kg/m^2)
- Normal renal function
Exclusion Criteria:
- Participants who currently smoke or use tobacco or nicotine products
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