A Study of Vismodegib With Surgery in Patients With Previously Untreated Basal Cell Carcinoma

Inclusion Criteria:

- Adult patients, >=18 years of age

- Diagnosis of non-infected, not recurrent, previously untreated basal cell carcinoma

- Free of any significant physical abnormalities (e.g., tattoos) at the target basal
cell carcinoma site

- Willing and able to participate in the study as an outpatient and agreement to make
frequent visits to the clinic during the treatment and follow-up periods and to
comply with study requirements

Exclusion Criteria:

- Prior treatment with vismodegib

- Known hypersensitivity to any of the study drug excipients

- Any metastatic basal cell carcinoma

- Any locally advanced basal cell carcinoma considered to be inoperable or to have a
medical contraindication to surgery

- Evidence of clinically significant and unstable diseases or conditions (e.g.,
cardiovascular, immunosuppressive, hematologic)

- Any dermatological disease at the target basal cell carcinoma site that may cause
difficulty with examination

- Recent, current, or planned participation in another experimental drug study