Mood and Nutrition Interventions in Polycystic Ovary Syndrome
| Status: | Completed |
|---|---|
| Conditions: | Peripheral Vascular Disease, Women's Studies |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Reproductive |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 11/24/2016 |
| Start Date: | July 2013 |
Improving Psychological Health and Cardiovascular Disease Risk in Women With PCOS
The purpose of this study is to help determine the best treatment plan for women with PCOS
who are overweight or obese and experiencing significant symptoms of depression and anxiety.
Specifically, the investigators are attempting to see if there is a difference between
cognitive behavioral therapy in combination with nutritional counseling in improving mood
symptoms, response to stress, and risk factors for heart disease compared to nutrition
counseling alone. The investigators hypothesize that combined treatment with Cognitive
Behavioral Therapy (CBT) and nutritional counseling will be more beneficial.
who are overweight or obese and experiencing significant symptoms of depression and anxiety.
Specifically, the investigators are attempting to see if there is a difference between
cognitive behavioral therapy in combination with nutritional counseling in improving mood
symptoms, response to stress, and risk factors for heart disease compared to nutrition
counseling alone. The investigators hypothesize that combined treatment with Cognitive
Behavioral Therapy (CBT) and nutritional counseling will be more beneficial.
This study will assess the impact of treatment of mood and associated anxiety disorders in
conjunction with nutritional/exercise counseling in overweight/obese women with PCOS on
cardiometabolic risk. The investigators hypothesize that women with PCOS will have greater
benefit from dual intervention (psychological and nutritional/exercise counseling) for
change in depressive symptoms and cardiometabolic risk reduction compared to
nutritional/exercise counseling alone. In addition, the investigators hypothesize that
psychological counseling may improve cardiometabolic risk by decreasing stress responses and
stress associated markers of inflammation.
conjunction with nutritional/exercise counseling in overweight/obese women with PCOS on
cardiometabolic risk. The investigators hypothesize that women with PCOS will have greater
benefit from dual intervention (psychological and nutritional/exercise counseling) for
change in depressive symptoms and cardiometabolic risk reduction compared to
nutritional/exercise counseling alone. In addition, the investigators hypothesize that
psychological counseling may improve cardiometabolic risk by decreasing stress responses and
stress associated markers of inflammation.
Inclusion Criteria:
- Diagnosis of Polycystic Ovary Syndrome (PCOS)
- Overweight or obese (BMI 27-50)
- Screen positive for symptoms of depression
Exclusion Criteria:
- Smoking 5 or more cigarettes per day
- Severe depression/anxiety warranting immediate treatment
- Actively participating in a weight loss program
- Taking medications to control cholesterol or diabetes
- On hormonal therapy (must be discontinued to be eligible)
- Pregnancy or planning to become pregnant during the study period
- Inability to commute to Philadelphia for weekly study sessions
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