Tofacitinib In Psoriatic Arthritis Subjects With Inadequate Response to TNF Inhibitors



Status:Completed
Conditions:Arthritis, Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery, Rheumatology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:August 2013
End Date:April 2016

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Phase 3, Randomized, Double-blind, Placebo-controlled Study Of The Efficacy And Safety Of 2 Doses Of Tofacitinib (Cp-690,550) In Subjects With Active Psoriatic Arthritis And An Inadequate Response To At Least One Tnf Inhibitor

To examine the safety and efficacy of tofacitinib in subjects with active psoriatic
arthritis who have previously had an inadequate response to at least one TNF inhibitor
either due to lack of efficacy or an adverse event.


Inclusion Criteria:

- Active arthritis at screening/baseline as indicated by >/= 3 tender/painful and 3
swollen joints

- Active plaque psoriasis at screening

- Inadequate efficacy or lack of toleration to previously administered TNF inhibitor

Exclusion Criteria:

- Non-plaque forms of psoriasis (with exception of nail psoriasis)

- History of autoimmune rheumatic disease other than PsA; also prior history of or
current, rheumatic inflammatory disease other than PsA
We found this trial at
41
sites
Brigham and Women's Hosp
75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
?
mi
from
Boston, MA
Click here to add this to my saved trials
Brigham and Women's Hosp
75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
?
mi
from
Boston, MA
Click here to add this to my saved trials
East Penn Rheumatology Associates, P.C.
Bethlehem, Pennsylvania 18015
?
mi
from
Bethlehem, PA
Click here to add this to my saved trials
Rheumatology Associates, PC
Birmingham, Alabama 35205
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
St. Luke's Intermountain Research Center
Boise, Idaho 83702
?
mi
from
Boise, ID
Click here to add this to my saved trials
Royal Prince Alfred Hospital, Rheumatology Department
Camperdown, New South Wales 2050
?
mi
from
Camperdown,
Click here to add this to my saved trials
Low Country Rheumatology
Charleston, South Carolina 29406
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Cincinnati Rheumatic Disease Study Group
Cincinnati, Ohio 45219
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
University Hospitals Case Medical Center - Department of Dermatology
Cleveland, Ohio 44106
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Adriana Pop-Moody MD - Clinic PA
Corpus Christi, Texas 78404
?
mi
from
Corpus Christi, TX
Click here to add this to my saved trials
Medvin Clinical Research
Covina, California 91723
?
mi
from
Covina, CA
Click here to add this to my saved trials
Metroplex Clinical Research Center
Dallas, Texas 75231
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Altoona Center for Clinical Research
Duncansville, Pennsylvania 16635
?
mi
from
Duncansville, PA
Click here to add this to my saved trials
St. Paul Rheumatology, PA
Eagan, Minnesota 55121
?
mi
from
Eagan, MN
Click here to add this to my saved trials
St. Jude Hospital Yorba Linda DBA St. Joseph Heritage Healthcare
Fullerton, California 92835
?
mi
from
Fullerton, CA
Click here to add this to my saved trials
Arizona Arthritis & Rheumatology Associates, PC
Glendale, Arizona 85304
?
mi
from
Glendale, AZ
Click here to add this to my saved trials
Klein & Associates MD, PA.
Hagerstown, Maryland 21740
?
mi
from
Hagerstown, MD
Click here to add this to my saved trials
Pioneer Research Solutions, Inc.
Houston, Texas 77098
?
mi
from
Houston, TX
Click here to add this to my saved trials
Rheumatology Associates Of North Alabama, P.C.
Huntsville, Alabama 35801
?
mi
from
Huntsville, AL
Click here to add this to my saved trials
Covance Central Laboratory Service
Indianapolis, Indiana 46214
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
The Arthritis Clinic
Jackson, Tennessee 38305
?
mi
from
Jackson, TN
Click here to add this to my saved trials
West Tennessee Research Institute
Jackson, Tennessee 38305
?
mi
from
Jackson, TN
Click here to add this to my saved trials
Dartmouth-Hitchcock Medical Center (DHMC)
Lebanon, New Hampshire 03756
?
mi
from
Lebanon, NH
Click here to add this to my saved trials
Bluegrass Community Research, Inc
Lexington, Kentucky 40504
?
mi
from
Lexington, KY
Click here to add this to my saved trials
Physician Research Collaboration
Lincoln, Nebraska 68512
?
mi
from
Lincoln, NE
Click here to add this to my saved trials
Ronald Reagan UCLA Medical Center - Drug Information Center
Los Angeles, California 90095
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Paramount Medical Research & Consulting, Llc
Middleburg Heights, Ohio 44130
?
mi
from
Middleburg Heights, OH
Click here to add this to my saved trials
Rheumatology Associates of Central Florida
Orlando, Florida 32806
?
mi
from
Orlando, FL
Click here to add this to my saved trials
Millennium Research
Ormond Beach, Florida 32174
?
mi
from
Ormond Beach, FL
Click here to add this to my saved trials
The Arthritis Center
Palm Harbor, Florida 34684
?
mi
from
Palm Harbor, FL
Click here to add this to my saved trials
Integral Rheumatology & Immunology Specialists (IRIS)
Plantation, Florida 33324
?
mi
from
Plantation, FL
Click here to add this to my saved trials
University of Utah Hospital and Clinics
Salt Lake City, Utah 84132
?
mi
from
Salt Lake City, UT
Click here to add this to my saved trials
Drug Shipment/Storage: Investigational Drug Services
Salt Lake City, Utah 84112
?
mi
from
Salt Lake City, UT
Click here to add this to my saved trials
San Diego Arthritis Medical Clinic
San Diego, California 92108
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Seattle Rheumatology Associates
Seattle, Washington 98104
?
mi
from
Seattle, WA
Click here to add this to my saved trials
Clayton Medical Research
St. Louis, Missouri 63117
?
mi
from
St. Louis, MO
Click here to add this to my saved trials
Stanford Hospital and Clinics
Stanford, California 94305
?
mi
from
Stanford, CA
Click here to add this to my saved trials
New England Research Associates, Llc
Trumbull, Connecticut 06611
?
mi
from
Trumbull, CT
Click here to add this to my saved trials
The Center for Rheumatology and Bone Research
Wheaton, Maryland 20902
?
mi
from
Wheaton, MD
Click here to add this to my saved trials
Clinical Pharmacology Study Group
Worcester, Massachusetts 01610
?
mi
from
Worcester, MA
Click here to add this to my saved trials
Florida Medical Clinic
Zephyrhills, Florida 33542
?
mi
from
Zephyrhills, FL
Click here to add this to my saved trials