Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery



Status:Completed
Conditions:Chronic Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:July 2013
End Date:August 2014

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A Multicenter, Prospective, Randomized, Double-blind Study to Determine the Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery

The purpose of this study is to assess the efficacy of intravenous ibuprofen compared to
ketorolac for the treatment of postoperative pain as measured by patient pain intensity
(Visual Analog Scale, VAS)


Inclusion Criteria:

- Patients scheduled for knee arthroscopy

Exclusion Criteria:

- Inadequate IV access.

- History of allergy or hypersensitivity to any component of ibuprofen, ketorolac,
aspirin (or aspirin related products), non-steroidal anti-inflammatory drugs
(NSAIDs), opioids or cyclooxygenase-2 (COX-2) inhibitors.

- Less than 18 years of age.

- Use of analgesics less than 8 hours prior to surgery.

- Patients with active, clinically significant anemia.

- History or evidence of asthma or heart failure.

- Pregnant.

- Recent history of chronic opioid use.

- Concomitant use of probenecid.

- Inability to understand the requirements of the study, be willing to provide written
informed consent (as evidenced by signature on an informed consent document approved
by an Institutional Review Board [IRB]), and agree to abide by the study restrictions
and to return for the required assessments.

- Refusal to provide written authorization for use and disclosure of protected health
information.
We found this trial at
4
sites
1653 W. Congress Parkway
Chicago, Illinois 60612
(312) 942-5000
Rush University Medical Center Rush University Medical Center encompasses a 664-bed hospital serving adults and...
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