Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery
Status: | Completed |
---|---|
Conditions: | Chronic Pain |
Therapuetic Areas: | Musculoskeletal |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 4/21/2016 |
Start Date: | July 2013 |
End Date: | August 2014 |
A Multicenter, Prospective, Randomized, Double-blind Study to Determine the Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery
The purpose of this study is to assess the efficacy of intravenous ibuprofen compared to
ketorolac for the treatment of postoperative pain as measured by patient pain intensity
(Visual Analog Scale, VAS)
ketorolac for the treatment of postoperative pain as measured by patient pain intensity
(Visual Analog Scale, VAS)
Inclusion Criteria:
- Patients scheduled for knee arthroscopy
Exclusion Criteria:
- Inadequate IV access.
- History of allergy or hypersensitivity to any component of ibuprofen, ketorolac,
aspirin (or aspirin related products), non-steroidal anti-inflammatory drugs
(NSAIDs), opioids or cyclooxygenase-2 (COX-2) inhibitors.
- Less than 18 years of age.
- Use of analgesics less than 8 hours prior to surgery.
- Patients with active, clinically significant anemia.
- History or evidence of asthma or heart failure.
- Pregnant.
- Recent history of chronic opioid use.
- Concomitant use of probenecid.
- Inability to understand the requirements of the study, be willing to provide written
informed consent (as evidenced by signature on an informed consent document approved
by an Institutional Review Board [IRB]), and agree to abide by the study restrictions
and to return for the required assessments.
- Refusal to provide written authorization for use and disclosure of protected health
information.
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Rush University Medical Center Rush University Medical Center encompasses a 664-bed hospital serving adults and...
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