Phosphatidylcholine Supplementation in Infants
| Status: | Not yet recruiting |
|---|---|
| Conditions: | Schizophrenia |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/21/2016 |
| Start Date: | October 2016 |
| End Date: | January 2031 |
| Contact: | Randal G Ross, MD |
| Email: | randy.ross@ucdenver.edu |
| Phone: | 303-724-6203 |
Phosphatidylcholine Supplementation in Infants With Diminished Sensory Gating
Sensory gating is defined as the automatic process of inhibiting brain response to repeated
auditory sounds. Infants who brains respond similarly to two identical sounds presented
about 1/2 second apart are more likely to have later problems with attention than infants
who suppress response to the second sound. This study will examine whether providing a
nutritional supplement, phosphatidylcholine, for two months in infancy will result in an
increased likelihood of developing more robust sensory gating.
auditory sounds. Infants who brains respond similarly to two identical sounds presented
about 1/2 second apart are more likely to have later problems with attention than infants
who suppress response to the second sound. This study will examine whether providing a
nutritional supplement, phosphatidylcholine, for two months in infancy will result in an
increased likelihood of developing more robust sensory gating.
Inclusion Criteria:
- Healthy infant has an age (adjusted for gestational age at birth) of 1-7 weeks
- Diminished P50 sensory gating (ratio greater than or equal to 0.50)
Exclusion Criteria:
- No maternal reported tobacco use for greater than 1 year and no current tobacco use
(as measured by urine cotinine levels)
- Trimethylaminuria, renal disease, liver disease, known chromosomal abnormality,
chronic neurological disorder, premature birth, prenatal exposure to exogenous
steroid use
We found this trial at
1
site
13001 E. 17th Pl
Aurora, Colorado 80045
Aurora, Colorado 80045
303-724-5000
Principal Investigator: Randal G Ross, MD
Phone: 303-724-6206
University of Colorado Denver The University of Colorado Denver | Anschutz Medical Campus provides a...
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