Thromboelastography During Surgery for Malignant Pleural Mesothelioma
| Status: | Completed |
|---|---|
| Conditions: | Lung Cancer, Cancer, Hematology |
| Therapuetic Areas: | Hematology, Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | September 2013 |
| End Date: | December 2015 |
Surgery for malignant pleural mesothelioma is complex and prolonged, and may involve
significant blood loss with considerable blood and product transfusion. Thromboelastography
(TEG) is a global assay of coagulation that uses whole blood to produce a tracing that
records kinetic changes in clot formation. This study aims provide a better understanding of
the coagulation profile of these patients, and will form the basis of a TEG-based
transfusion algorithm for future surgeries for mesothelioma.
significant blood loss with considerable blood and product transfusion. Thromboelastography
(TEG) is a global assay of coagulation that uses whole blood to produce a tracing that
records kinetic changes in clot formation. This study aims provide a better understanding of
the coagulation profile of these patients, and will form the basis of a TEG-based
transfusion algorithm for future surgeries for mesothelioma.
Thromboelastography can provide more in-depth and quicker analysis of the complex
coagulation processes during surgery
coagulation processes during surgery
Inclusion Criteria:
- Adult male or female patients undergoing elective surgery for malignant pleural
mesothelioma
Exclusion Criteria:
- Unwilling or unable to provide consent
- History of bleeding disorder
- On medications that may affect hemostasis
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