Characterization of Familial Myopathy and Paget Disease of Bone
| Status: | Suspended |
|---|---|
| Conditions: | Neurology |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 2/27/2019 |
| Start Date: | June 2010 |
| End Date: | June 2020 |
Phase 1 Study Non-invasive Use Diffuse Optical Spectroscopy Will Measure the Concentrations of Blood, Water, and Lipids (Fats, for Example) in Tissues
The researcher wants to explore the genetic causes of muscle disease. The researcher is
particularly interested in muscle disorders that occur in combination with diseases of bone
that appear to be passed on from generation to generation.
Diffuse Optical Spectroscopy will measure the concentrations of blood, water, and lipids
(fats, for example) in your tissues. This device essentially measures the color of tissues in
order to determine tissue physiology (its physical and chemical processes).
particularly interested in muscle disorders that occur in combination with diseases of bone
that appear to be passed on from generation to generation.
Diffuse Optical Spectroscopy will measure the concentrations of blood, water, and lipids
(fats, for example) in your tissues. This device essentially measures the color of tissues in
order to determine tissue physiology (its physical and chemical processes).
Diffuse Optical Spectroscopy, the technique is fast and painless and was developed at the
University of California, Irvine. The Diffuse Optical Spectroscopy instrument is actively
involved in research studies, but is not yet a part of routine clinical practice. The result
of this study will aid similar research projects that seek to improve our understanding of
how tissues work and how alterations in metabolism affect long-term health.
TheDiffuse Optical Spectroscopy measurement consists of placing a probe onto the surface of
your body (calf, bicep, or head). This probe will be secured by either gentle hand pressure
or fastened to your skin using clinically-approved wraps such as Coban/wrap bandages or
medical adhesive tape and medical glues. Several dots will be made on your skin outlining the
probe with a surgical felt tip marker. This is so we would be able to put the probe again on
the same spot in case we needed to interrupt the measurement. The probe looks like a bar code
scanner in a supermarket and it shines infrared light on your skin. There is no radiation
involved with this light. In some cases where light signals are low, the optical detector
will be placed directly onto your skin (but contained within an electronically shielded
casing, and placed inside another plastic casing). (not offered during pregnancy).
University of California, Irvine. The Diffuse Optical Spectroscopy instrument is actively
involved in research studies, but is not yet a part of routine clinical practice. The result
of this study will aid similar research projects that seek to improve our understanding of
how tissues work and how alterations in metabolism affect long-term health.
TheDiffuse Optical Spectroscopy measurement consists of placing a probe onto the surface of
your body (calf, bicep, or head). This probe will be secured by either gentle hand pressure
or fastened to your skin using clinically-approved wraps such as Coban/wrap bandages or
medical adhesive tape and medical glues. Several dots will be made on your skin outlining the
probe with a surgical felt tip marker. This is so we would be able to put the probe again on
the same spot in case we needed to interrupt the measurement. The probe looks like a bar code
scanner in a supermarket and it shines infrared light on your skin. There is no radiation
involved with this light. In some cases where light signals are low, the optical detector
will be placed directly onto your skin (but contained within an electronically shielded
casing, and placed inside another plastic casing). (not offered during pregnancy).
Inclusion Criteria: Male or Female age 18 and older
- diagnose of Muscle or bone disorders
- with a combination of medical problems including muscle and bone disease and their
family members.
Exclusion Criteria:
- under 18 year of age
- unrelated diagnosis
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