Walking While Talking: The Effect of Doing Two Things at Once in Individuals With Neurological Injury or Disease



Status:Suspended
Conditions:Parkinsons Disease, Hospital, Neurology, Neurology, Neurology, Neurology, Multiple Sclerosis
Therapuetic Areas:Neurology, Other
Healthy:No
Age Range:18 - 90
Updated:9/8/2018
Start Date:April 2013
End Date:December 15, 2021

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Walking While Talking: The Effects of Dual Task on Gait and Cognition in Individuals With Neurological Injury or Disease.

This study will evaluate gait when individuals with Parkinson's disease (PD) are walking
while talking to see how walking changes when challenged to perform a functional cognitive
task simultaneously. By looking at walking alone and walking with varying cognitive loads the
investigators will be able to determine motor and cognitive factors vulnerable to
interference in PD. Each is important to understand so that training can address components
of walking that become impaired when someone is distracted by a common cognitive task and so
that the intensity of treatment matches the level of task difficulty. Using this initial
data, the investigators will establish a protocol to improve walking taking into account the
unique features of PD, including bradykinesia, freezing of gait, stiffness, and problems with
memory and attention. The investigators will evaluate the potential for this treatment to
improve walking and improve or maintain cognitive abilities necessary to multitask.

In this study participants will be asked to participate in a training study to examine
whether a new walking intervention that combines cognitive training with walking on a
treadmill improves walking more than gait training or cognitive training alone. Participants
with Parkinson's disease (PD) will come to the lab for a complete gait assessment using a
motion analysis system that will record leg motion and muscle activity during comfortable
walking. During the initial evaluation, participants will also complete cognitive assessments
and surveys about community activities and quality of life related to PD. Participants will
be divided into one of the three training groups and asked to come to the lab three times a
week for four weeks during the intervention. One week and one month after training,
participants will return to the lab to complete all the same assessments that were performed
during the initial visit. The results of the three testing sessions (initial, one week and
one month) will be compared between and within groups to see if any of the interventions
provided unique benefits to the health of persons with PD.

Inclusion Criteria:

- Clinical diagnosis of Parkinson's disease, mild traumatic brain injury, multiple
sclerosis or Huntington's disease

- ambulatory for at least 200 feet without an assistive device (cane, walker, etc)

Exclusion Criteria:

- recent orthopedic injury (e.g., fracture, sprain, muscle pull, herniated disc)

- concurrent neurological illnesses including stroke, brain cancer, spinal cord injury,
and diabetic neuropathies.

- cardiac insufficiency limiting ability to participate in walking study
We found this trial at
1
site
Stony Brook, New York 11794
Principal Investigator: Lisa Muratori, PT, EdD
Phone: 631-444-6583
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Stony Brook, NY
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