TMS for CRPS - Pilot Study



Status:Recruiting
Conditions:Chronic Pain, Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:18 - Any
Updated:3/1/2014
Start Date:July 2013
Contact:Sean Mackey, MD, PhD
Email:smackey@stanford.edu

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The purpose of this pilot study is to test whether Transcranial Magnetic Stimulation (TMS)
may alleviate the symptoms of Complex Regional Pain Syndrome (CRPS). The investigators will
test various methods of TMS in a small pilot study to investigate what methods may have
clinical potential. This is a small pilot study to determine feasibility and signal to
potentially inform future trials.


Inclusion Criteria:

1. Age 18 or older

2. Diagnosis of CRPS (complex regional pain syndrome)

3. Average pain level reported on Numerical Rating Scale meets entry criteria

4. Ability to perform the experimental task and procedures.

Exclusion Criteria:

1. MRI contraindication (metal implants or devices, claustrophobia)

2. TMS Contraindication (eg metal implant or devices near the site of stimulation)

3. History of epilepsy

4. History of a psychological or psychiatric disorder that would interfere with study
procedures, at the discretion of the researcher.

5. Neurologic illness that would interfere with brain integrity

6. Current medical condition or medication use that would interfere with study
procedures or data integrity, at the discretion of the researcher.

7. Currently pregnant or planning to become pregnant.

8. On going legal action or disability claim.
We found this trial at
1
site
Palo Alto, California 94304
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Palo Alto, CA
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