Fluid Intake Application to Reduce Kidney Stone Risks



Status:Enrolling by invitation
Conditions:Nephrology, Nephrology, Nephrology
Therapuetic Areas:Nephrology / Urology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:July 2013
End Date:August 2016

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Do Different Methods of Educating Patients Regarding Fluid Intake Reduce Kidney Stone Risks?

The purpose of this investigation is to prospectively evaluate the benefit of different
methods of educating patients regarding their fluid intake through a readily available daily
cellular phone application to improve overall urine output and reduce risk factors for stone
recurrence.

The prevalence of kidney stone disease in the United States is increasing. Recurrence of
kidney stone disease has been reported as high as 50% at five years. Urine supersaturation
is a predominant factor in the formation of crystallization and stone disease and is
dependent on fluid volume. High fluid consumption that dilutes the urine has been shown both
in vitro and in clinical studies to reduce the tendency for stone crystallization as well as
effectively decrease stone recurrence. As a result, water intake greater than two liters per
day is a common initial therapy for prevention of stone disease. However, studies have shown
that despite physician counseling most patients are only able to modestly increase their
urine volume through fluid intake. This finding may be due to a discrepancy in patient
perception of their actual fluid intake and resulting urine volume. The purpose of this
investigation is to prospectively evaluate the benefit of different methods of educating
patient regarding their fluid intake through a readily available daily cellular phone
application to improve overall urine output and reduce risk factors for stone recurrence.

Inclusion Criteria:

1. Patients ≥ 18 years old

2. Seen in urology or nephrology clinic at UNC with a diagnosis of kidney stone

3. Prior 24-hour urine result with volume less than 2 to 2.5 liters

Exclusion Criteria:

1. Patient without cellular phone capable of utilizing Android / Apple application

2. Patient already using some form of monitoring fluid intake / volume

3. Inability to take fluid by mouth

4. Patient with urinary diversion, chronic diarrhea, bowel diversion or other forms of
excessive fluid loss

5. Inability to obtain informed consent

6. Non-English speaking
We found this trial at
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Chapel Hill, North Carolina 27599
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Chapel Hill, NC
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