Beans/Bran Enriching Nutritional Eating For Intestinal Health Trial

Objectives:

1. To learn about how increased cooked navy bean powders or rice bran dietary intake
affect the stool microbiota of colorectal cancer survivors and healthy adults.

2. To determine whether cooked navy bean powders or rice bran consumption modulate
microbial metabolism.

3. To observe dietary changes in the blood, urine and stool metabolite profiles and
inflammatory cytokines.

Inclusion Criteria:

- ≥ 18 years of age.

- Be a Colorectal Cancer Survivor that is a minimum of 4 months post
chemotherapy/radiation treatment. OR be a healthy adult with no prior history of
treatment for cancer.

- BMI between 25-35

- no previous or concurrent malignancy except for adequately treated basal cell or
squamous cell skin cancer, in situ cervical cancer and other cancer for which the
patient has been disease free for five years.

- Ability to complete questionnaire(s) and dietary food logs

- Willingness to consume meals/snacks provided for 28 consecutive days

- Drink less than or equal to one alcoholic drink/day

Exclusion Criteria:

- History of food allergies and/or major dietary restrictions

- Pregnant or lactating or planning to become pregnant

- Self identified as a smoker

- Taking prescribed medication to control their lipids

- Taking Bean-O, other anti-flatulence medications or prolonged antibiotic use (one
month)

- Have a history of gallstones.