Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment



Status:Completed
Conditions:Insomnia Sleep Studies, Pulmonary
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - 75
Updated:7/19/2018
Start Date:June 2013
End Date:April 2015

Use our guide to learn which trials are right for you!

Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With Positive Airway Pressure Treatment

Our group has recently found that the choice of positive airway pressure mask can
significantly affect the pressure required to adequately treat sleep disordered breathing.
The goal of this study is to visualize the upper airway in the retropalatal and retroglossal
region while using both oronasal and nasal masks with CPAP in order to investigate
differences in upper airway dynamics that may occur between these two mask types.

It is known that oronasal masks are not as effective at opening the upper airway compared to
nasal only continuous positive airway pressure (CPAP) masks in patients with sleep-disordered
breathing. However, the physiological mechanism for this difference in efficacy is not known;
although, it has been hypothesized to involve the retroglossal and/or retropalatal region of
the upper airway. The objective of this study was to investigate differences in retroglossal
and retropalatal anterior-posterior space with the use of oronasal vs. nasal CPAP masks using
real-time cine magnetic resonance imaging (cMRI).

Inclusion Criteria:

- AHI> 30/hr

- 18-75 years of age

Exclusion Criteria:

- History of claustrophobia

- History of pacemaker, nerve stimulator, or any other metal implanted device
We found this trial at
1
site
New York, New York 10065
?
mi
from
New York, NY
Click here to add this to my saved trials