CCTG 593: Testing and Linkage to Care

Design: CCTG 593 is a project to evaluate the uptake and effectiveness of an ALERT
specialist serving to

1. link newly diagnosed, HIV infected persons from HIV testing sites to HIV specialist
providers, and

2. link confirmed HIV antibody negative persons with continued high risk behaviors to PrEP
centers

Duration: Each subject who agrees to linkage will receive ALERT follow-up until successful
linkage or 60 days following enrollment for linkage to care or 90 days following enrollment
for linkage to PrEP, whichever comes first. The duration of the 593 project will be for 3.5
years or until all subjects have been enrolled and successfully linked, or 60 days pass for
linkage to care or 90 days for linkage to PrEP.

Sample Size: Up to 600 subjects will be tested and offered linkage across all CCTG sites: LA
County-USC Medical Center, Harbor-UCLA/City of Long Beach Department of Health and Human
Services, UCSD/San Diego Health and Human Services Agency.

Study Population: Eligible subjects will include any persons 18 years of age or older who
have been tested for HIV at one of the CCTG testing sites (LA County + USC, Long Beach
Department of Health and Human Services, and San Diego Health and Human Services Agency).

Inclusion Criteria:

- Age 18 years or older

- Has had an HIV test result form the CCTG Consortium testing site as either positive
or negative

- Ability to provide informed consent

- English or Spanish Speaking

Exclusion Criteria:

- Severe active substance abuse or mental illness that the investigator feels will
interfere with the ability to provide informed consent

- Acute medical illness that requires transfer to a non CCTG hospital