Biomarkers In Retinitis Pigmentosa (BIRP)



Status:Active, not recruiting
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:18 - 100
Updated:8/20/2016
Start Date:September 2013
End Date:December 2018

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In this study, markers of oxidative stress will be measured in the aqueous humour and plasma
of RP patients compared to controls.

People with Retinitis Pigmentosa have loss of night vision followed by loss of central
vision due to damage and death of photoreceptors. One of the mechanisms causing damage is
high levels of oxygen in the eye. This damage produces specific biomarkers which can be
measured. In this study, these biomarkers will be assessed in people with Retinitis
Pigmentosa and compared to controls.

Inclusion Criteria:

- Signed informed consent and authorization of use and disclosure of protected health
information

- Age more than or equal to 18 years

- For the study group, patients diagnosed with Retinitis Pigmentosa by the
investigators

- For the control group, patients undergoing vitreoretinal surgery for macular hole,
epiretinal membrane, vitreomacular traction, retinal detachment, neovascular AMD and
Diabetic Retinopathy will be eligible

Exclusion Criteria:

- Patients with active or suspected ocular or periocular infection
We found this trial at
1
site
Baltimore, Maryland
Principal Investigator: Peter Campochiaro, MD
?
mi
from
Baltimore, MD
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