Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery
| Status: | Withdrawn |
|---|---|
| Conditions: | Orthopedic |
| Therapuetic Areas: | Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 18 - 80 |
| Updated: | 4/21/2016 |
| Start Date: | June 2015 |
| End Date: | June 2015 |
Randomized, Double-Blinded, Placebo-controlled Study to Evaluate the Analgesic Efficacy of Oral Clonidine and Gabapentin as Part of a Multi-modal Analgesic Regimen for Preventing Pain After Arthroscopic Shoulder or Knee Surgery
The purpose of this research is to investigate the non-opioid (non-narcotic) pain-relieving
medications clonidine and gabapentin to see if they decrease the amount of opioid pain
medications needed after surgery, thereby reducing opioid-related side effects, and time
required to return to normal activities of daily living after surgery.
medications clonidine and gabapentin to see if they decrease the amount of opioid pain
medications needed after surgery, thereby reducing opioid-related side effects, and time
required to return to normal activities of daily living after surgery.
Inclusion Criteria:
- Patients scheduled to undergo arthroscopic joint surgery
- Willingness and ability to sign an informed consent document
- No allergies to clonidine, gabapentin, anesthetic or analgesic medications
- 18 - 80 years of age
- American Society of Anesthesiologists (ASA) Class I - III adults of either sex
- Women of childbearing potential must be currently practicing an acceptable form of
birth control, and have a negative urine pregnancy test
Exclusion Criteria:
- Patients with known allergy, hypersensitivity or contraindications to clonidine,
gabapentin, anesthetic or analgesic medications
- Patients with clinically-significant medical conditions, such as brain, heart,
kidney, endocrine, or liver diseases, peptic ulcer disease or bleeding disorders
- Patients with chronic hypertension or pain syndromes receiving clonidine or
gabapentin, respectively.
- Pregnant or lactating women
- Subjects with a history of alcohol or drug abuse within the past 3 months
- Patients taking any analgesic medications within 48 hours prior to the surgery
- Any other conditions or use of any medication which may interfere with the conduct of
the study
- Non-English speakers
- Patients greater than 80 years of age
We found this trial at
1
site
Cedars Sinai Med Ctr Cedars-Sinai is known for providing the highest quality patient care. Our...
Click here to add this to my saved trials
