Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 Diabetes
Status: | Completed |
---|---|
Conditions: | Diabetes, Diabetes |
Therapuetic Areas: | Endocrinology |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 2/3/2018 |
Start Date: | December 2, 2013 |
End Date: | December 11, 2014 |
This trial is conducted globally. The aim of the trial is to examine the dose range,
escalation and efficacy of oral semaglutide in subjects with type 2 diabetes.
escalation and efficacy of oral semaglutide in subjects with type 2 diabetes.
Inclusion Criteria:
- BMI above or equal to 25 and below or equal to 40 kg/m^2
- Subjects diagnosed with T2D (Type 2 diabetes) treated with diet and exercise and/or
who have been on a stable dose of metformin for at least 30 days prior to screening
- HbA1c 7.0-9.5% (53-80 mmol/mol) (both inclusive)
Exclusion Criteria:
- Subjects on selected oral medication with a narrow therapeutic window, such as
warfarin, digoxin, tricyclic antidepressants, lithium, aminophylline, theophylline and
anticonvulsants
- History of chronic pancreatitis or idiopathic acute pancreatitis
- Chronic malabsorption, regardless of aetiology
- History of Crohn's disease, ulcerative colitis, or other inflammatory bowel disease
- Treatment with glucose lowering agent(s) other than metformin as stated in the
inclusion criteria in a period of 90 days before the screening visit
We found this trial at
38
sites
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