Crossover Study to Evaluate the Efficacy, Safety and Tolerability of Different Doses of Indacaterol in Patients With Persistent Asthma



Status:Completed
Conditions:Asthma
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - Any
Updated:5/5/2014
Start Date:November 2013
End Date:April 2014
Contact:Novartis Pharmaceuticals
Phone:1-888-669-6682

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A Multicenter, Randomized, Double-blind, Placebo-controlled, Crossover Study to Evaluate the Efficacy, Safety and Tolerability of Five Different Doses of Inhaled Indacaterol (QAB149) Delivered Via the Single Dose Dry Powder Inhaler (SDDPI) in Patients With Persistent Asthma

The purpose of this study is to determine the efficacy of indacaterol 55µg once daily (and
27.5 µg twice) in QVA149 compared to 75 µg indacaterol monotherapy.


Inclusion Criteria:

- Asthma for at least 6 months, using inhaled corticosteroid for at least one month,
foreced breath test less than below the normal value of the general population, -show
an immediate improvement in breathing when given albuterol

Exclusion Criteria:

- patients who have smoked in the past 6 months or are currently smoking, including
those who smoked more than a pack of cigarettes a day for at least 10 years,
-patients who have a history of life-threatening asthma, -patients who have had an
astham attack, in the last 6 weeks, requiring use of systemic steroids,
hospitalization, or ER visit, -patients who have had a respiratory tract infection or
worsening asthma between screening or run-in periods, patients requring use of other
asthma-related drugs during the trial, other protocol-defined inclusion/exclusion may
apply
We found this trial at
12
sites
El Paso, Texas 79902
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Centennial, Colorado 80112
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Dallas, Texas 75216
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Huntington Beach, California 92647
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Los Angeles, California 90095
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Medford, Oregon 97504
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Medford, OR
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Mission Viejo, California 92691
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North Dartmouth, Massachusetts 02747
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North Dartmouth, MA
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Portland, Oregon 97228
Novartis Novartis, which was created in 1996 by the merger of the Swiss companies Ciba-Geigy...
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Raleigh, North Carolina 27609
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Raleigh, NC
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Skillman, New Jersey 08558
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Skillman, NJ
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St. Louis, Missouri 63110
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St. Louis, MO
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