A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events



Status:Completed
Conditions:Diabetes, Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:50 - Any
Updated:3/21/2019
Start Date:October 29, 2013
End Date:October 16, 2016

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This trial is conducted globally. The aim of this trial is to compare cardiovascular safety
of insulin degludec versus insulin glargine in subjects with type 2 diabetes at high risk of
cardiovascular events.


Inclusion Criteria: - Type 2 diabetes - Age above or equal to 50 years with predefined
previous cardiovascular disease(s) or renal disease or age above or equal to 60 years with
predefined cardiovascular risk factors - HbA1c (glycosylated haemoglobin) above or equal to
7.0% or HbA1c below 7.0% and current insulin treatment corresponding to above or equal to
20 U of basal insulin per day - One or more oral or injectable antidiabetic agent(s)
Exclusion Criteria: - An acute coronary or cerebrovascular event in the previous 60 days -
Planned coronary, carotid or peripheral artery revascularisation - Chronic heart failure
NYHA (New York Heart Association) class IV - Current or past (within the last 5 years)
malignant neoplasms (except basal cell and squamous cell skin carcinoma)
We found this trial at
213
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Fresno, California 93702
1988
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Addison, Illinois 60101
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Atlanta, Georgia 30318
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Bennington, Vermont 05201
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Boca Raton, Florida 33433
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Buckley, Michigan 49620
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Burlington, North Carolina 27215
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Champaign, Illinois 61821
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Chula Vista, California 91910
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Downey, California 90242
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Duarte, California 91010
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Dunwoody, Georgia 30338
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Elkhorn, Nebraska 68022
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Encino, California 91436
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Hermitage, Pennsylvania 16148
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Huntington Beach, California 92648
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La Jolla, California 92037
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