A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events



Status:Completed
Conditions:Diabetes, Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:50 - Any
Updated:3/21/2019
Start Date:October 29, 2013
End Date:October 16, 2016

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This trial is conducted globally. The aim of this trial is to compare cardiovascular safety
of insulin degludec versus insulin glargine in subjects with type 2 diabetes at high risk of
cardiovascular events.


Inclusion Criteria: - Type 2 diabetes - Age above or equal to 50 years with predefined
previous cardiovascular disease(s) or renal disease or age above or equal to 60 years with
predefined cardiovascular risk factors - HbA1c (glycosylated haemoglobin) above or equal to
7.0% or HbA1c below 7.0% and current insulin treatment corresponding to above or equal to
20 U of basal insulin per day - One or more oral or injectable antidiabetic agent(s)
Exclusion Criteria: - An acute coronary or cerebrovascular event in the previous 60 days -
Planned coronary, carotid or peripheral artery revascularisation - Chronic heart failure
NYHA (New York Heart Association) class IV - Current or past (within the last 5 years)
malignant neoplasms (except basal cell and squamous cell skin carcinoma)
We found this trial at
213
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Shreveport, Louisiana 71105
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Addison, Illinois 60101
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