Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis (IPF)
| Status: | Recruiting |
|---|---|
| Conditions: | Pulmonary |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 10/13/2018 |
| Start Date: | October 2005 |
| End Date: | July 2020 |
| Contact: | Melinda J Klesen, BA |
| Email: | klesenmj@upmc.edu |
| Phone: | 412-802-6860 |
Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis
The purpose of the study is to identify genetic and biologic markers that may predict the
loss of lung function due to idiopathic pulmonary fibrosis. The studies will compare genetic
and biologic markers of samples to changes in symptoms. The ultimate goal is to predict if or
when patients are likely to experience a rapid decline in lung function due to disease
progression.
loss of lung function due to idiopathic pulmonary fibrosis. The studies will compare genetic
and biologic markers of samples to changes in symptoms. The ultimate goal is to predict if or
when patients are likely to experience a rapid decline in lung function due to disease
progression.
People who are diagnosed with idiopathic pulmonary fibrosis are asked to participate in this
study. The subject must be treated at the Dorothy P. and Richard P. Simmons Center for
Interstitial Lung Disease. Subjects, if consented, are required to perform tests so that
research data can be collected. At the initial visit, patients are subject to having a blood
draw, pulmonary function testing, echocardiograms, and CT scans as well as completing several
questionnaires designed to measure how the patient is feeling. Follow up visits are then
scheduled in 3-4 month intervals. Every 3-4 months blood samples will be collected while
every 6-8 months the questionnaires will administered. If the patient enters a stage of
accelerated decline in lung function, a bronchoscopy will be performed to collect residual
bronchoalveolar lavage fluid for testing. All of the results of clinical and laboratory
testing will be placed into the subjects research file.
study. The subject must be treated at the Dorothy P. and Richard P. Simmons Center for
Interstitial Lung Disease. Subjects, if consented, are required to perform tests so that
research data can be collected. At the initial visit, patients are subject to having a blood
draw, pulmonary function testing, echocardiograms, and CT scans as well as completing several
questionnaires designed to measure how the patient is feeling. Follow up visits are then
scheduled in 3-4 month intervals. Every 3-4 months blood samples will be collected while
every 6-8 months the questionnaires will administered. If the patient enters a stage of
accelerated decline in lung function, a bronchoscopy will be performed to collect residual
bronchoalveolar lavage fluid for testing. All of the results of clinical and laboratory
testing will be placed into the subjects research file.
Inclusion Criteria:
- Patients who are 18 or older
- Diagnosis of Idiopathic Pulmonary Fibrosis
- Treated at the Simmons Center
Exclusion Criteria:
- Other Lung Illness
We found this trial at
1
site
4200 Fifth Ave
Pittsburgh, Pennsylvania 15260
Pittsburgh, Pennsylvania 15260
(412) 624-4141
Phone: 412-802-6860
University of Pittsburgh The University of Pittsburgh is a state-related research university, founded as the...
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