Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events



Status:Completed
Conditions:High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:8/2/2018
Start Date:October 29, 2013
End Date:July 10, 2017

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Phase 3 Double-blind, Randomized, Placebo-controlled, Parallel-group Study To Assess The Efficacy, Long-term Safety And Tolerability Of Pf-04950615 In Subjects With Primary Hyperlipidemia Or Mixed Dyslipidemia At Risk Of Cardiovascular Events

This study is a multicenter, randomized study in subjects with high cholesterol receiving
highly effective statins to assess the efficacy, safety and tolerability of Bococizumab
(PF-04950615;RN316) to lower LDL-C.


Inclusion Criteria:

- Treated with a statin.

- Fasting LDL-C > 70 mg/dL and triglyceride <=400 mg/dL.

- High or very high risk of incurring a cardiovascular event.

Exclusion Criteria:

- Pregnant or breastfeeding females.

- Cardiovascular or cerebrovascular event of procedures during the past 30 days.

- Congestive heart failure NYHA class IV.

- Poorly controlled hypertension.
We found this trial at
156
sites
North Alabama Research Center
Athens, Alabama 35811
661
mi
from
Athens, AL
Click here to add this to my saved trials
Avail Clinical Research
860 Peachwood Drive
DeLand, Florida 32720
(386) 740-0770
Site Overview Avail Clinical Research is a renowned and experienced clinical research site conducting Phase...
1123
mi
from
DeLand, FL
Click here to add this to my saved trials
Upstate Pharmaceutical Research
30 Pointe Circle
Greenville, South Carolina 29615
(864)255-3540
883
mi
from
Greenville, SC
Click here to add this to my saved trials
AGA Clinical Trials
900 W 49th St # 430
Hialeah, Florida 33012
1312
mi
from
Hialeah, FL
Click here to add this to my saved trials
Baylor College of Medicine
1200 Moursund Street
Houston, Texas 77030
(713) 798-4951
Baylor College of Medicine Baylor College of Medicine in Houston, the only private medical school...
569
mi
from
Houston, TX
Click here to add this to my saved trials
International Research Associates
8200 SW 117th Ave # 210
Miami, Florida 33183
1316
mi
from
Miami, FL
Click here to add this to my saved trials
Radiant Research, Inc.
Akron, Ohio 44311
898
mi
from
Akron, OH
Click here to add this to my saved trials
Albany Medical College Division of Community Endocrinology
Albany, New York 12206
1308
mi
from
Albany, NY
Click here to add this to my saved trials
KRK Medical Research
Arlington, Texas 76012
347
mi
from
Arlington, TX
Click here to add this to my saved trials
Ernest L. Hendrix, MD, PC
108 Sanders Street
Athens, Alabama 35611
636
mi
from
Athens, AL
Click here to add this to my saved trials
Atlanta Diabetes Associates
Atlanta, Georgia 30309
800
mi
from
Atlanta, GA
Click here to add this to my saved trials
ACRC - Cardiology
Atlantis, Florida 33462
1287
mi
from
Atlantis, FL
Click here to add this to my saved trials
Care Clinical Research Corporation
Banning, California 92220
1097
mi
from
Banning, CA
Click here to add this to my saved trials
Southern Maine Health Care
Biddeford, Maine 04005
1481
mi
from
Biddeford, ME
Click here to add this to my saved trials
Alabama Internal Medicine, PC
Birmingham, Alabama 35235
683
mi
from
Birmingham, AL
Click here to add this to my saved trials
Drug Shipment and Study Conducted at Address: University of Alabama at Birmingham
Birmingham, Alabama 35294
683
mi
from
Birmingham, AL
Click here to add this to my saved trials
Kirklin Clinic
Birmingham, Alabama 35233
684
mi
from
Birmingham, AL
Click here to add this to my saved trials
Northwest Clinical Trials
Boise, Idaho 83704
1046
mi
from
Boise, ID
Click here to add this to my saved trials
Drug Trials Brooklyn
Brooklyn, New York 12230
1056
mi
from
Brooklyn, NY
Click here to add this to my saved trials
Investigator's Research Group
Brownsburg, Indiana
631
mi
from
Brownsburg, IN
Click here to add this to my saved trials
Community Health Care, Inc.
Canal Fulton, Ohio 44614
893
mi
from
Canal Fulton, OH
Click here to add this to my saved trials
Med Center
Carmichael, California 95608
1274
mi
from
Carmichael, CA
Click here to add this to my saved trials
Radiant Research Incorporated
Chandler, Arizona 85224
846
mi
from
Chandler, AZ
Click here to add this to my saved trials
Coastal Cardiology
Charleston, South Carolina
1063
mi
from
Charleston, SC
Click here to add this to my saved trials
Sensenbrenner Primary Care
Charlotte, North Carolina 28277
958
mi
from
Charlotte, NC
Click here to add this to my saved trials
IHA Chelsea Family & Internal Medicine
Chelsea, Michigan 48118
?
mi
from
Chelsea, MI
Click here to add this to my saved trials
Sterling Research Group
Cincinnati, Ohio 45219
725
mi
from
Cincinnati, OH
Click here to add this to my saved trials
The Lindner Center for Research and Education at The Christ Hospital
Cincinnati, Ohio 45219
725
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Metabolic And Atherosclerosis Research Center
Cincinnati, Ohio 45212
729
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Sentral Clinical Research Services - Admin Only
Cincinnati, Ohio 45236
728
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Sentral Clinical Research Services, LLC
Cincinnati, Ohio 45236
726
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Sterling Research Group
Cincinnati, Ohio 45219
725
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Morton Plant Mease Health Care, Inc. Cardiovascular Research
1200 Druid Road South
Clearwater, Florida 33756
1101
mi
from
Clearwater, FL
Click here to add this to my saved trials
Clinicos, LLC
Colorado Springs, Colorado 80904
386
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
Clinical Research Advantage, Inc. / Colorado Springs Health Partners, SW
Colorado Springs, Colorado 80906
386
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
Columbia Medical Practice
Columbia, Maryland 21045
1135
mi
from
Columbia, MD
Click here to add this to my saved trials
West Broadway Clinic
Council Bluffs, Iowa 51501
260
mi
from
Council Bluffs, IA
Click here to add this to my saved trials
North Texas Healthcare System, Dallas VAMC
Dallas, Texas 75216
347
mi
from
Dallas, TX
Click here to add this to my saved trials
Research Institute of Dallas
Dallas, Texas 75231
342
mi
from
Dallas, TX
Click here to add this to my saved trials
Brandywine Clinical Research
Downingtown, Pennsylvania 19335
1196
mi
from
Downingtown, PA
Click here to add this to my saved trials
Altoona Center for Clinical Research
Duncansville, Pennsylvania 16635
1053
mi
from
Duncansville, PA
Click here to add this to my saved trials
Radiant Research, Inc.
Edina, Minnesota 55435
544
mi
from
Edina, MN
Click here to add this to my saved trials
Liberty Family Practice
Erie, Pennsylvania 16508
983
mi
from
Erie, PA
Click here to add this to my saved trials
Med Investigations
Fair Oaks, California 95628
1271
mi
from
Fair Oaks, CA
Click here to add this to my saved trials
QUEST Research Institute
Farmington Hills, Michigan 48334
830
mi
from
Farmington Hills, MI
Click here to add this to my saved trials
Fleming Island Center for Clinical Research
Fleming Island, Florida 32003
1061
mi
from
Fleming Island, FL
Click here to add this to my saved trials
Invesclinic, LLC
Fort Lauderdale, Florida 33308
1306
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
University of North Texas Health Science Center at Fort Worth
Fort Worth, Texas 76107
347
mi
from
Fort Worth, TX
Click here to add this to my saved trials
Florida Research Network
Gainesville, Florida 32605
1049
mi
from
Gainesville, FL
Click here to add this to my saved trials
Advanced Research Associates
Glendale, Arizona 85308
852
mi
from
Glendale, AZ
Click here to add this to my saved trials
Pharmquest
Greensboro, North Carolina 27408
999
mi
from
Greensboro, NC
Click here to add this to my saved trials
Drug Trials America
Hartsdale, New York 10530
1298
mi
from
Hartsdale, NY
Click here to add this to my saved trials
The Research Center
Hialeah, Florida 33016
1309
mi
from
Hialeah, FL
Click here to add this to my saved trials
Homestead Medical Research
Homestead, Florida 33030
1323
mi
from
Homestead, FL
Click here to add this to my saved trials
East-West Medical Research Institute
Honolulu, Hawaii 96814
3717
mi
from
Honolulu, HI
Click here to add this to my saved trials
Northwest Houston Cardiology
Houston, Texas 77070
572
mi
from
Houston, TX
Click here to add this to my saved trials
Texas Center for Drug Development, P.A.
Houston, Texas
569
mi
from
Houston, TX
Click here to add this to my saved trials
Pioneer Research Solutions, Inc.
Houston, Texas 77098
570
mi
from
Houston, TX
Click here to add this to my saved trials
lnvestigational Drug Services (IDA)
Houston, Texas 77030
572
mi
from
Houston, TX
Click here to add this to my saved trials
California Heart Specialists
Huntington Beach, California 92648
1164
mi
from
Huntington Beach, CA
Click here to add this to my saved trials
Alia Clinical research Inc
Huntington Park, California 90255
1168
mi
from
Huntington Park, CA
Click here to add this to my saved trials
Heart Center Research, Llc
Huntsville, Alabama 35801
660
mi
from
Huntsville, AL
Click here to add this to my saved trials
American Health Network
Indianapolis, Indiana 46254
638
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Midwest Institute for Clinical Research
Indianapolis, Indiana 46260
643
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Nature Coast Clinical Research
Inverness, Florida 34452
1084
mi
from
Inverness, FL
Click here to add this to my saved trials
University of Iowa College of Public Health - Preventive Intervention Center
Iowa City, Iowa 52242
428
mi
from
Iowa City, IA
Click here to add this to my saved trials
Westside Center for Clinical Research
Jacksonville, Florida 32205
1055
mi
from
Jacksonville, FL
Click here to add this to my saved trials
East Coast Institute for Research, LLC at Baker-Gilmour Cardiovascular Institute, PA
Jacksonville, Florida 32216
1055
mi
from
Jacksonville, FL
Click here to add this to my saved trials
East Coast Institute for Research, LLC at Jacksonville Cardiovascular Center
Jacksonville, Florida 32216
1055
mi
from
Jacksonville, FL
Click here to add this to my saved trials
East Coast Institute for Research, LLC at Northeast Florida Endocrine & Diabetes Associates
Jacksonville, Florida 32204
1054
mi
from
Jacksonville, FL
Click here to add this to my saved trials
St. Vincent's Cardiology
Jacksonville, Florida 32216
1055
mi
from
Jacksonville, FL
Click here to add this to my saved trials
East Coast Institute for Research, LLC at Northeast Florida Cardiology Clinic
3550 University Boulevard South
Jacksonville, Florida 32216
1060
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Westside Family Medical Center
Kalamazoo, Michigan 49009
718
mi
from
Kalamazoo, MI
Click here to add this to my saved trials
University of Kansas Medical Center
3901 Rainbow Blvd
Kansas City, Kansas 66160
(913) 588-5000
University of Kansas Medical Center The University of Kansas Medical Center serves Kansas through excellence...
190
mi
from
Kansas City, KS
Click here to add this to my saved trials
KCUMB Center for Community and Clinical Research
Kansas City, Missouri 64106
198
mi
from
Kansas City, MO
Click here to add this to my saved trials
Cardiovascular Research of Knoxville
Knoxville, Tennessee 37917
777
mi
from
Knoxville, TN
Click here to add this to my saved trials
New Orleans Center for Clinical Research
Knoxville, Tennessee 37920
777
mi
from
Knoxville, TN
Click here to add this to my saved trials
Volunteer Research Group
Knoxville, Tennessee 37920
779
mi
from
Knoxville, TN
Click here to add this to my saved trials
Detweiler Family Medicine and Associates, PC
Lansdale, Pennsylvania 19446
1219
mi
from
Lansdale, PA
Click here to add this to my saved trials
OM Medical
Las Vegas, Nevada 89119
962
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Clinical Research of South Nevada
Las Vegas, Nevada 89121
958
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Sjh Cardiology Associates
Liverpool, New York 13088
1192
mi
from
Liverpool, NY
Click here to add this to my saved trials
Downtown L.A. Research Center, Inc.
Los Angeles, California 90017
1169
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Richard S Cherlin
Los Gatos, California 95032
1319
mi
from
Los Gatos, CA
Click here to add this to my saved trials
Manassas Clinical Research Center
Manassas, Virginia 20110
1103
mi
from
Manassas, VA
Click here to add this to my saved trials
Clinical Research Institute of Southern Oregon, PC
Medford, Oregon 97504
1355
mi
from
Medford, OR
Click here to add this to my saved trials
Suburban Research Associates
Media, Pennsylvania 19063
1212
mi
from
Media, PA
Click here to add this to my saved trials
Solaris Clinical Research
Meridian, Idaho 83646
1053
mi
from
Meridian, ID
Click here to add this to my saved trials
Arizona Center For Internal Medicine
Mesa, Arizona 85205
835
mi
from
Mesa, AZ
Click here to add this to my saved trials
Omega Clinical Research, Llc
Metairie, Louisiana 70006
693
mi
from
Metairie, LA
Click here to add this to my saved trials
San Marcus Research Clinic
Miami, Florida 33015
1308
mi
from
Miami, FL
Click here to add this to my saved trials
Clinical Research Of Miami, Inc.
Miami, Florida 33126
1321
mi
from
Miami, FL
Click here to add this to my saved trials
Finlay Medical Research
Miami, Florida 33126
1316
mi
from
Miami, FL
Click here to add this to my saved trials
Medical Research Center
286 Westward Drive
Miami, Florida 33144
1315
mi
from
Miami, FL
Click here to add this to my saved trials
Kendall South Medical Center, Inc.
Miami, Florida 33175
1313
mi
from
Miami, FL
Click here to add this to my saved trials
Crossroads Clinical Research, Inc.
Mooresville, North Carolina 28117
953
mi
from
Mooresville, NC
Click here to add this to my saved trials
Radiant Research, Inc.
Murray, Utah 84123
780
mi
from
Murray, UT
Click here to add this to my saved trials
Hill Country Medical Associates
New Braunfels, Texas 78130
556
mi
from
New Braunfels, TX
Click here to add this to my saved trials
Rutgers Biomedical and Health Sciences - Robert Wood Johnson Medical School
New Brunswick, New Jersey 08901
1263
mi
from
New Brunswick, NJ
Click here to add this to my saved trials
New Orleans Center for Clinical Research
New Orleans, Louisiana 70119
696
mi
from
New Orleans, LA
Click here to add this to my saved trials
Mid Hudson Medical Research
New Windsor, New York 12553
1286
mi
from
New Windsor, NY
Click here to add this to my saved trials