Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events



Status:Completed
Conditions:High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:8/2/2018
Start Date:October 29, 2013
End Date:July 10, 2017

Use our guide to learn which trials are right for you!

A Phase 3 Double-blind, Randomized, Placebo-controlled, Parallel-group Study To Assess The Efficacy, Long-term Safety And Tolerability Of Pf-04950615 In Subjects With Primary Hyperlipidemia Or Mixed Dyslipidemia At Risk Of Cardiovascular Events

This study is a multicenter, randomized study in subjects with high cholesterol receiving
highly effective statins to assess the efficacy, safety and tolerability of Bococizumab
(PF-04950615;RN316) to lower LDL-C.


Inclusion Criteria:

- Treated with a statin.

- Fasting LDL-C > 70 mg/dL and triglyceride <=400 mg/dL.

- High or very high risk of incurring a cardiovascular event.

Exclusion Criteria:

- Pregnant or breastfeeding females.

- Cardiovascular or cerebrovascular event of procedures during the past 30 days.

- Congestive heart failure NYHA class IV.

- Poorly controlled hypertension.
We found this trial at
156
sites
Knoxville, Tennessee 37920
?
mi
from
Knoxville, TN
Click here to add this to my saved trials
860 Peachwood Drive
DeLand, Florida 32720
(386) 740-0770
Site Overview Avail Clinical Research is a renowned and experienced clinical research site conducting Phase...
?
mi
from
DeLand, FL
Click here to add this to my saved trials
30 Pointe Circle
Greenville, South Carolina 29615
(864)255-3540
?
mi
from
Greenville, SC
Click here to add this to my saved trials
900 W 49th St # 430
Hialeah, Florida 33012
?
mi
from
Hialeah, FL
Click here to add this to my saved trials
1200 Moursund Street
Houston, Texas 77030
(713) 798-4951
Baylor College of Medicine Baylor College of Medicine in Houston, the only private medical school...
?
mi
from
Houston, TX
Click here to add this to my saved trials
8200 SW 117th Ave # 210
Miami, Florida 33183
?
mi
from
Miami, FL
Click here to add this to my saved trials
Akron, Ohio 44311
?
mi
from
Akron, OH
Click here to add this to my saved trials
?
mi
from
Albany, NY
Click here to add this to my saved trials
Arlington, Texas 76012
?
mi
from
Arlington, TX
Click here to add this to my saved trials
Athens, Alabama 35811
?
mi
from
Athens, AL
Click here to add this to my saved trials
108 Sanders Street
Athens, Alabama 35611
?
mi
from
Athens, AL
Click here to add this to my saved trials
Atlanta, Georgia 30309
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Atlantis, Florida 33462
?
mi
from
Atlantis, FL
Click here to add this to my saved trials
Banning, California 92220
?
mi
from
Banning, CA
Click here to add this to my saved trials
Biddeford, Maine 04005
?
mi
from
Biddeford, ME
Click here to add this to my saved trials
Birmingham, Alabama 35235
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Birmingham, Alabama 35233
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Boise, Idaho 83704
?
mi
from
Boise, ID
Click here to add this to my saved trials
Brooklyn, New York 12230
?
mi
from
Brooklyn, NY
Click here to add this to my saved trials
Brownsburg, Indiana
?
mi
from
Brownsburg, IN
Click here to add this to my saved trials
Canal Fulton, Ohio 44614
?
mi
from
Canal Fulton, OH
Click here to add this to my saved trials
Carmichael, California 95608
?
mi
from
Carmichael, CA
Click here to add this to my saved trials
Chandler, Arizona 85224
?
mi
from
Chandler, AZ
Click here to add this to my saved trials
Charleston, South Carolina
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Charlotte, North Carolina 28277
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
Chelsea, Michigan 48118
?
mi
from
Chelsea, MI
Click here to add this to my saved trials
Cincinnati, Ohio 45219
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Cincinnati, Ohio 45219
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
1200 Druid Road South
Clearwater, Florida 33756
?
mi
from
Clearwater, FL
Click here to add this to my saved trials
Colorado Springs, Colorado 80904
?
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
?
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
Columbia, Maryland 21045
?
mi
from
Columbia, MD
Click here to add this to my saved trials
Council Bluffs, Iowa 51501
?
mi
from
Council Bluffs, IA
Click here to add this to my saved trials
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Dallas, Texas 75231
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Downingtown, Pennsylvania 19335
?
mi
from
Downingtown, PA
Click here to add this to my saved trials
Duncansville, Pennsylvania 16635
?
mi
from
Duncansville, PA
Click here to add this to my saved trials
Edina, Minnesota 55435
?
mi
from
Edina, MN
Click here to add this to my saved trials
Erie, Pennsylvania 16508
?
mi
from
Erie, PA
Click here to add this to my saved trials
Fair Oaks, California 95628
?
mi
from
Fair Oaks, CA
Click here to add this to my saved trials
Farmington Hills, Michigan 48334
?
mi
from
Farmington Hills, MI
Click here to add this to my saved trials
Fleming Island, Florida 32003
?
mi
from
Fleming Island, FL
Click here to add this to my saved trials
Fort Lauderdale, Florida 33308
?
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
?
mi
from
Fort Worth, TX
Click here to add this to my saved trials
Gainesville, Florida 32605
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
Glendale, Arizona 85308
?
mi
from
Glendale, AZ
Click here to add this to my saved trials
Greensboro, North Carolina 27408
?
mi
from
Greensboro, NC
Click here to add this to my saved trials
Hartsdale, New York 10530
?
mi
from
Hartsdale, NY
Click here to add this to my saved trials
Hialeah, Florida 33016
?
mi
from
Hialeah, FL
Click here to add this to my saved trials
Homestead, Florida 33030
?
mi
from
Homestead, FL
Click here to add this to my saved trials
Honolulu, Hawaii 96814
?
mi
from
Honolulu, HI
Click here to add this to my saved trials
Houston, Texas 77070
?
mi
from
Houston, TX
Click here to add this to my saved trials
?
mi
from
Houston, TX
Click here to add this to my saved trials
Houston, Texas 77098
?
mi
from
Houston, TX
Click here to add this to my saved trials
?
mi
from
Houston, TX
Click here to add this to my saved trials
Huntington Beach, California 92648
?
mi
from
Huntington Beach, CA
Click here to add this to my saved trials
Huntington Park, California 90255
?
mi
from
Huntington Park, CA
Click here to add this to my saved trials
Huntsville, Alabama 35801
?
mi
from
Huntsville, AL
Click here to add this to my saved trials
Indianapolis, Indiana 46254
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Indianapolis, Indiana 46260
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Inverness, Florida 34452
?
mi
from
Inverness, FL
Click here to add this to my saved trials
?
mi
from
Iowa City, IA
Click here to add this to my saved trials
Jacksonville, Florida 32205
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Jacksonville, Florida 32216
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
3550 University Boulevard South
Jacksonville, Florida 32216
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Kalamazoo, Michigan 49009
?
mi
from
Kalamazoo, MI
Click here to add this to my saved trials
3901 Rainbow Blvd
Kansas City, Kansas 66160
(913) 588-5000
University of Kansas Medical Center The University of Kansas Medical Center serves Kansas through excellence...
?
mi
from
Kansas City, KS
Click here to add this to my saved trials
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Knoxville, Tennessee 37917
?
mi
from
Knoxville, TN
Click here to add this to my saved trials
Knoxville, Tennessee 37920
?
mi
from
Knoxville, TN
Click here to add this to my saved trials
Lansdale, Pennsylvania 19446
?
mi
from
Lansdale, PA
Click here to add this to my saved trials
Las Vegas, Nevada 89119
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Las Vegas, Nevada 89121
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Liverpool, New York 13088
?
mi
from
Liverpool, NY
Click here to add this to my saved trials
Los Angeles, California 90017
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Los Gatos, California 95032
?
mi
from
Los Gatos, CA
Click here to add this to my saved trials
Manassas, Virginia 20110
?
mi
from
Manassas, VA
Click here to add this to my saved trials
?
mi
from
Medford, OR
Click here to add this to my saved trials
Media, Pennsylvania 19063
?
mi
from
Media, PA
Click here to add this to my saved trials
Meridian, Idaho 83646
?
mi
from
Meridian, ID
Click here to add this to my saved trials
?
mi
from
Mesa, AZ
Click here to add this to my saved trials
Metairie, Louisiana 70006
?
mi
from
Metairie, LA
Click here to add this to my saved trials
Miami, Florida 33015
?
mi
from
Miami, FL
Click here to add this to my saved trials
Miami, Florida 33126
?
mi
from
Miami, FL
Click here to add this to my saved trials
Miami, Florida 33126
?
mi
from
Miami, FL
Click here to add this to my saved trials
286 Westward Drive
Miami, Florida 33144
?
mi
from
Miami, FL
Click here to add this to my saved trials
Miami, Florida 33175
?
mi
from
Miami, FL
Click here to add this to my saved trials
Mooresville, North Carolina 28117
?
mi
from
Mooresville, NC
Click here to add this to my saved trials
Murray, Utah 84123
?
mi
from
Murray, UT
Click here to add this to my saved trials
New Braunfels, Texas 78130
?
mi
from
New Braunfels, TX
Click here to add this to my saved trials
?
mi
from
New Brunswick, NJ
Click here to add this to my saved trials
New Orleans, Louisiana 70119
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
New Windsor, New York 12553
?
mi
from
New Windsor, NY
Click here to add this to my saved trials