A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia
| Status: | Completed |
|---|---|
| Conditions: | High Cholesterol |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 6/15/2016 |
| Start Date: | October 2013 |
| End Date: | April 2016 |
A 52 Week, Phase 3 Double-blind, Randomized, Placebo-controlled, Parallel-group Study To Assess The Efficacy, Safety And Tolerability Of Pf-04950615 In Subjects With Heterozygous Familial Hypercholesterolemia
This is a multicenter, randomized study in subjects with heterozygous familial
hypercholesterolemia receiving highly effective statins to assess the safety, efficacy and
tolerability of Bococizumab (PF-04950615; RN316) to lower LDL-C.
hypercholesterolemia receiving highly effective statins to assess the safety, efficacy and
tolerability of Bococizumab (PF-04950615; RN316) to lower LDL-C.
Inclusion Criteria:
- Treated with a statin.
- Fasting LDL-C > 70 mg/dL and triglyceride <=400 mg/dL.
- High or very high risk of incurring a cardiovascular event.
- Heterozygous familial hypercholesterolemia.
Exclusion Criteria:
- Pregnant or breastfeeding females.
- Cardiovascular or cerebrovascular event of procedures during the past 30 days.
- Congestive heart failure NYHA class IV.
- Poorly controlled hypertension.
We found this trial at
23
sites
The Hartford Hospital Hartford Hospital is the major teaching hospital affiliated with the University of...
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Chapel Hill, North Carolina 27599
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Chapel Hill, North Carolina 27599
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U.T. Southwestern Medical Center The story of UT Southwestern Medical Center is one of commitment...
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Thomas Jefferson University We are dedicated to the health sciences and committed to educating professionals,...
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