Evaluate Esophageal Reinforcement With ACell MatriStem Surgical Matrix: A Degradable Biologic Scaffold Material

Inclusion Criteria:

- Patient 18 years of age or older

- Pathologically confirmed Gastric, Gastroesophageal Junction (GEJ) or Esophageal,
adenocarcinoma at either MSKCC or a participating site (biopsy may be performed at
other institutions but slides must be confirmed at MSKCC or a participating site, as
is routine care at our institution)

- Patient undergoing any resection requiring an anastomosis to the esophagus for
curative intent. Including but not limited to esophagectomy or total gastrectomy.

- Subject is willing to provide written informed consent

- Subject is willing and able to comply with the follow-up regimen

Exclusion Criteria:

- Pregnant or lactating women

- Intraoperative evidence of metastatic or locally-unresectable disease

- Patients with known sensitivity or allergy to porcine materials.

- Patients undergoing any resection requiring an anastomosis to the esophagus for
palliative intent.