Foot/Hand Neuromodulation for Overactive Bladder (OAB)

Foot neuromodulation is designed to treat OAB conditions by electrically stimulating the
somatic afferent nerves in the foot using skin surface electrodes. The foot stimulation is
non-invasive, can be performed at home, and has no adverse effects. Foot neuromodulation
therapy will likely be accepted by more patients and have the potential to make a broader
impact on the improvement of OAB conditions.

Inclusion Criteria:

1. 18 year old men and women and older

2. Currently having overactive bladder (OAB) symptoms, i.e. urgency, frequency, or
incontinence

3. No evidence of neurological disorder or urinary tract infection, i.e. clinically
diagnosed as idiopathic OAB

Exclusion Criteria:

1. Pregnant women in their late pregnancy phase will be excluded because the increasing
size of the baby/uterus may cause overactive bladder.

2. Patients with implanted electrical stimulators such as pacemaker will be excluded for
potential interference with the TENS stimulator.

3. Patients who are allergic to Cipro or Bactrim will be excluded from the CMG study.