Safety and Tolerability of Initiating LCZ696 in Heart Failure Patients

Inclusion Criteria:

- Age ≥ 18 years; CHF with New York Heart Association class II-IV; left ventricular
ejection fraction ≤ 35%; on beta blockers

Exclusion Criteria:

- Potassium > 5.2 mmol/l; estimated glomerular filtration rate < 30 ml/min/1.73 m2;
systolic blood pressure <100 mmHg or > 180 mmHg; history of intolerance to
recommended target doses of angiotensin converting enzyme inhibitors or angiotensin
receptor blockers

Other protocol-defined inclusion/exclusion criteria may apply.