Efficacy of Buffered Lidocaine in Patients With Facial Swelling
| Status: | Completed |
|---|---|
| Conditions: | Other Indications, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 10/14/2017 |
| Start Date: | March 2013 |
| End Date: | June 2014 |
Anesthetic Efficacy of 4% Buffered Lidocaine in Emergency Patients With Facial Swelling.
The purpose of this study is to determine the clinical efficacy of a buffered 4% lidocaine
solution for incision and drainage. Ninety patients will be examined clinically to determine
a diagnosis of cellulitis or fluctuance. The diagnosis will be confirmed by incision and
drainage. Patients will receive either 3.6 ml 4% lidocaine with 1:100,000 epinephrine or 3.6
ml 4% lidocaine with 1:100,000 epinephrine buffered with 8.4% sodium bicarbonate. Patients
will rate pain prior to and throughout the procedure.
solution for incision and drainage. Ninety patients will be examined clinically to determine
a diagnosis of cellulitis or fluctuance. The diagnosis will be confirmed by incision and
drainage. Patients will receive either 3.6 ml 4% lidocaine with 1:100,000 epinephrine or 3.6
ml 4% lidocaine with 1:100,000 epinephrine buffered with 8.4% sodium bicarbonate. Patients
will rate pain prior to and throughout the procedure.
Incision and drainage of swellings is painful and anesthetic failure is common. One reason
may be related to the lowered pH of inflamed tissue reducing the amount of the base form of
anesthetic. A buffered anesthetic solution may result in more effective anesthesia than a
non-buffered solution.
may be related to the lowered pH of inflamed tissue reducing the amount of the base form of
anesthetic. A buffered anesthetic solution may result in more effective anesthesia than a
non-buffered solution.
Inclusion Criteria:
- 18 years or older
- in good health (ASA classification I or II)
- able to give informed consent
- necrotic tooth with associated facial swelling
Exclusion Criteria:
- allergies to local anesthetics or sulfites
- history of significant medical problems (ASA classification III or greater)
- pregnancy
- inability to give informed consent
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