DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty



Status:Completed
Conditions:Hematology
Therapuetic Areas:Hematology
Healthy:No
Age Range:18 - 80
Updated:4/2/2016
Start Date:December 2013
End Date:July 2015

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A Prospective Randomized Trial for the Use of DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty.

This is study looking at the use of a medication, Desmopressin acetate (DDAVP), to reduce
bleeding, swelling, and bruising in patients undergoing cosmetic nose surgery. DDAVP is a
drug used in patients with bleeding disorders. It works by activating molecules in the blood
stream called platelets that promote clotting. In the study, participants who are have
cosmetic nose surgery (rhinoplasty) will be randomly assigned to receive or not receive
medication. Photographs taken before and shortly after surgery will be evaluated for the
amount of bruising and swelling. Patients with heart, lung, kidney, or liver problems are
not eligible to participate.


Inclusion Criteria:

- Undergoing Rhinoplasty where nasal bone osteotomy is necessary

Exclusion Criteria:

- Heart Disease

- Renal Disease with decreased GFR

- Liver Disease
We found this trial at
1
site
Lyndhurst, Ohio 44124
?
mi
from
Lyndhurst, OH
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