Functional MRI Use in Prostate Radiation Treatment Planning
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Prostate Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | July 2012 |
A Prospective Study Evaluating Non-Endorectal Coil Functional MRI Identification of Intraprostatic Tumor During Radiation Treatment Planning
This study is being done to evaluate the use of MRI during radiation treatment planning to
identify areas of tumor within the prostate to aid in future treatment planning and
targeting of prostate cancer. This study will be conducted at the University of Pennsylvania
Health System. The study is projected to run for 18 months. Subjects will be male 18 or
older with a prostate cancer diagnosis and treatment plansat the Department of Radiation
Oncology.
identify areas of tumor within the prostate to aid in future treatment planning and
targeting of prostate cancer. This study will be conducted at the University of Pennsylvania
Health System. The study is projected to run for 18 months. Subjects will be male 18 or
older with a prostate cancer diagnosis and treatment plansat the Department of Radiation
Oncology.
Inclusion Criteria:
- Age 18 or older
- Male
- Biopsy proven prostate cancer without evidence of metastatic disease
- Planned definitive external beam RT with daily ERB and implanted Visicoil fiducial
markers.
- Prior fMRI-ec documenting an IPL 25 mm2 in axial bidimensional diameter product,
concordant with intraprostatic tumor location as documented on transrectal
ultrasoundbiopsy
- Subject capable of giving informed consent for standard external beam RT and for the
study.
- No current contraindication that would prevent MRI or gadolinium contrast.
Exclusion Criteria:
- Metastatic disease
- Lack of fMRI-ec documeneting an IPL 25 mm2 in axial bidimensional product, concordant
with intraprostatic tumor location as documented on transrectal untrasound biopsy
- Neoadjuvant androgen deprivation therapy greater than 10 weeks, defined from date of
LHRH analog injection to date of fMRI-sim
- Contraindication that would prevent MRI or gadolinium contrast
- GFR 30 mL/min/1.73m2 per Crockoft-Gault formula.
We found this trial at
1
site
3400 Civic Center Blvd
Philadelphia, Pennsylvania 19104
Philadelphia, Pennsylvania 19104
(215) 662-6065
Abramson Cancer Center of the University of Pennsylvania The Abramson Cancer Center of the University...
Click here to add this to my saved trials
