Telemonitoring Enhanced Support for Depression Self Management

This project will test a practical intervention that uses low cost technologies to activate
depressed patients' existing social networks for self-management support. The intervention
links patients with a "CarePartner" (CP), i.e., a non-household family member or close friend
who is willing to support the patient in coordination with the clinician and any existing
in-home caregiver (ICG). Through weekly automated telemonitoring, patients report their mood
and self-management status, and receive tailored guidance on self-management. The CP receives
a corresponding update along with guidance on how to best support the patient's
self-management efforts, and the primary care team is notified about clinically urgent
situations. The intervention will be tested among depressed primary care patients from
clinics serving low-income and underinsured patients, whom the intervention was especially
designed to benefit. Specific Aim 1 is to conduct a randomized controlled trial to compare
the effectiveness of one year of telemonitoring-supported CP for depression versus usual care
(control) on depression severity. Specific Aim 2 is to examine key secondary outcomes
(response and remission, impairment, well-being, caregiving burden, healthcare costs) and
potential moderators. Specific Aim 3 is to use a mixed-methods approach to enrich our
interpretation of the statistical associations, and to discover strategies to enhance the
intervention's acceptability, effectiveness, and sustainability. If the intervention proves
effective without increasing clinician burden or marginal costs, then its subsequent
implementation could yield major public health benefits, especially in medically underserved
populations.

NOTE: In order to participate, must have received medical care for past year at one of the
participating clinics: Alcona Health Center, Cherry Street Health Services, Dua Family
Practice, Morang Chester

Additional Inclusion Criteria:

- at least 2 outpatient primary care visits in the past 2 years, 1 within the past 13
months

- depression diagnosis in medical chart problem list or billing record (ICD9 codes:
296.20-.26, .30-.36, 296.4-.9, 298.0, 300.4, 309.0-.1, 309.28, 311.00) during the past
2 years

- current PHQ >10 (non-mild depressive symptoms)

- at least 21 years old

- comfortable speaking English

- can use a touch-tone phone

- can identify at least 1 eligible CarePartner

- not in palliative care, on transplant waitlist, or <1 year life expectancy

- free of major cognitive impairment or psychiatrically unstable

- not experiencing domestic abuse or stalking

Exclusion Criteria:

- Limited life expectancy (e.g., advanced stage cancer/heart failure/on oxygen/end stage
renal disease), receiving palliative care

- At risk for domestic abuse, PHQ<10, end stage renal disease, lung cancer, dementia,
bipolar disease, schizophrenia, limited life expectancy (advanced stage cancer/heart
failure/on oxygen), alcohol problems, receiving palliative care

- Unable to speak English

- Not planning to get all or most of care at study site

- Primary care physician not affiliated with study site

- Unable to use telephone to respond to weekly automated self-management support calls

- Unable to nominate an eligible CP