Pancreatic Resection, Malnutrition and Readmission



Status:Completed
Conditions:Cancer, Cancer, Food Studies, Pancreatic Cancer
Therapuetic Areas:Oncology, Pharmacology / Toxicology
Healthy:No
Age Range:18 - Any
Updated:11/30/2016
Start Date:December 2013
End Date:June 2016

Use our guide to learn which trials are right for you!

Pancreatic Resection, Malnutrition, and Readmission: Assessment and Prevention

The Whipple procedure is associated with increased readmission rates for infection,
pancreatic leak, and failure to thrive/malnutrition. The purpose of this study is to develop
an evidence based perioperative nutrition plan to improve patient outcomes. The study has
two specific aims including evaluation of feasibility of implementing an evidence based
perioperative nutritional plan for patients undergoing Whipple and evaluation of impact of a
standard perioperative nutritional plan on primary outcome of readmission rate and secondary
outcomes of readmission cause, length of stay for initial hospitalization and/or
readmission, post surgical complications (surgical site infections, pancreatic leak, sepsis,
delayed gastric emptying), and nutritional status (PG-Subject Generated Assessment scores,
BMI, albumin, pre-albumin, and method of oral intake). Categorical variables including
readmission rate, readmission cause, post-surgical complications and nutritional status will
be compared by chi-square test between intervention and control group. Length of stay for
initial hospitalization and readmission will be compared by non parametric Wilcoxon test
between two groups. Descriptive statistics will be used to describe the sample. There are no
risks to the study participants.


Inclusion Criteria:

- Adult patients (>18 years of age)at Duke Cancer Center

- Malignant pancreatic disease, undergoing surgical resection with
pancreaticoduodenectomy (Whipple)

- Able to read and speak English.

Exclusion Criteria:

- Patients receiving preoperative enteral nutrition

- Inability to tolerate preoperative oral intake
We found this trial at
1
site
2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Principal Investigator: Kara L Penne, RN, MSN, ANP, AOCNP
Phone: 919-681-7348
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
?
mi
from
Durham, NC
Click here to add this to my saved trials