Building Employment Skills Through Therapy for Veterans



Status:Active, not recruiting
Conditions:Schizophrenia, Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - 65
Updated:4/6/2019
Start Date:June 12, 2015
End Date:August 31, 2020

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Integrated Cognitive Behavior Therapy to Improve Work Outcomes in Schizophrenia

Schizophrenia/Schizoaffective Disorder is associated with serious problems with cognitive
skills, social skills, and functional skills (like employment). There is a new form of
cognitive behavioral therapy called integrated cognitive behavioral therapy (iCBT) that
specifically addresses the cognitive, social, and functional deficits of
schizophrenia/schizoaffective disorder. This study is to compare iCBT to the usual care (UC)
that Veteran's receive. The investigators will compare iCBT to UC in subjects with
schizophrenia/schizoaffective disorder who are enrolled in a Supported Employment (SE)
program, and evaluate whether iCBT is more helpful in improving job performance, and other
areas of functioning, both right after treatment, and 6 months after the end of treatment.

The objective of the current proposal is to evaluate whether integrated cognitive behavior
therapy (iCBT) can improve engagement and success in an existing Supported Employment (SE)
program among the most functionally disabled patients with schizophrenia/schizoaffective
disorder. The iCBT condition also includes computerized cognitive remediation. The primary
specific aim is to determine whether iCBT will significantly improve work outcomes at
post-treatment to a greater extent than Usual Care (UC) in low functioning patients with
schizophrenia/schizoaffective disorder who join the SE program. The secondary aims are to
evaluate the whether iCBT will significantly improve work outcomes at 6 month follow-up
relative to UC, and whether iCBT will improve functional outcomes post-treatment and at
follow-up relative to UC in subjects who join the SE program.

Inclusion Criteria:

- Diagnosis of DSM-IV schizophrenia or schizoaffective disorder (SCID)

- Severe/extreme functional disability [World Health Organization Disability Assessment
Scale (WHODAS) score > 50]

- Clinical stability (as per primary mental health provider)

- Receiving treatment at the Veterans Administration

- Minimal engagement in psychiatric rehabilitation services (just psychiatrist and
therapist/case management in the last 6 months)

- Eligible for and willing to be enrolled in Supported Employment program

- Age 18 to 65

- Proficient in English

- Able to give informed consent

Exclusion Criteria:

- Neurologic disease or damage that would make the diagnosis of schizophrenia
questionable

- Current opioid or stimulant dependence (SCID)

- Not appropriate due to safety concerns (based on risk assessment)
We found this trial at
1
site
3900 Woodland Avenue
Philadelphia, Pennsylvania 19104
Principal Investigator: Steven L. Sayers, PhD
Phone: 215-823-5870
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mi
from
Philadelphia, PA
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