Prevalence of MTHFR Polymorphisms in Venous Disease



Status:Completed
Conditions:Cardiology, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:2/7/2015
Start Date:February 2011
End Date:December 2014
Contact:Stephen Varvel, PhD
Email:svarvel@hdlabinc.com
Phone:804-343-2718

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Prevalence of MTHFR Polymorphisms in Venous Disease With or Without Concomitant Thrombosis

The etiologies of varicose veins and the progression to more serious forms of chronic venous
disease and identification of appropriate diagnostic tests to better aid patient management
by identifying individuals who may benefit from more aggressive treatment and/ or
prophylactic measures.


Inclusion Criteria:

- Age 18 or over

- No venous disease (N=30); or C2-C3 venous disease (N=30); or C4-C6 venous disease
(N=30)

Exclusion Criteria:

- Pregnancy

- Cancer

- Chronic obstructive pulmonary disease (COPD)

- Any systemic inflammatory disease

- Any of the following within the previous 30 days:

- Trauma

- Any surgery

- Periods of prolonged inactivity
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