Intratumoral Cancer Chemotherapy Through a Flexible Bronchoscope as an Adjunct to Brachytherapy
Status: | Archived |
---|---|
Conditions: | Lung Cancer, Cancer |
Therapuetic Areas: | Oncology |
Healthy: | No |
Age Range: | Any |
Updated: | 7/1/2011 |
This study is being conducted in order to determine if intratumoral chemotherapy will be
helpful in the palliation of endobronchial tumors when used in conjunction with
endobronchial brachytherapy.
Injections of cisplatin are given in conjunction with the brachytherapy procedure. If the
direct intratumoral injections result in a decrease in the endobronchial obstructed airways
and if the therapy is well tolerated, there will be immediate clinical benefit to this
minimally invasive method, the most obvious being an improved quality of life.
Approximately 2 mg cisplatin per cubic centimeter of tumor are injected into each tumor
through a flexible bronchoscope. A total of four to six injections are administered one
week apart. Response to therapy is assessed based on improvement in intraluminal
obstruction by tumor, as assessed by endobronchial observation.
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