Fasting Predictors of OGTT and MMTT Response
| Status: | Recruiting |
|---|---|
| Conditions: | High Blood Pressure (Hypertension), Obesity Weight Loss, Peripheral Vascular Disease, Endocrine, Diabetes |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Endocrinology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 2/8/2015 |
| Start Date: | August 2013 |
| End Date: | August 2018 |
| Contact: | Stephen Varvel, PhD |
| Email: | svarvel@hdlabinc.com |
| Phone: | 804-343-2718 |
Identification of Fasting Biomarkers That Predict Responses to the Oral Glucose Tolerance Test (OGTT) and Mixed Meal Tolerance Test (MMTT)
1. To develop a database containing matched information from dynamic tests of postprandial
glycemic control (OGTT or MMTT), results of a broad panel of fasting biomarkers, and
clinical information related to diabetes risk obtain through subject interview.
2. To use the database to identify fasting biomarkers and associated algorithms to best
predict parameters derived from dynamic tests (OGTT or MMTT) such as Insulin Glucose
Tolerance (IGT), impaired first phase insulin response, etc., controlling for clinical
information such as current medication use.
glycemic control (OGTT or MMTT), results of a broad panel of fasting biomarkers, and
clinical information related to diabetes risk obtain through subject interview.
2. To use the database to identify fasting biomarkers and associated algorithms to best
predict parameters derived from dynamic tests (OGTT or MMTT) such as Insulin Glucose
Tolerance (IGT), impaired first phase insulin response, etc., controlling for clinical
information such as current medication use.
Inclusion Criteria:
- Weight >95
Exclusion Criteria:
- Prior diagnosis of Diabetes
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