The Cancer of the Pancreas Screening-5 CAPS5)Study

Status:	Recruiting
Conditions:	Cancer, Cancer, Other Indications
Therapuetic Areas:	Oncology, Other
Healthy:	No
Age Range:	18 - Any
Updated:	3/7/2019
Start Date:	January 2014
End Date:	December 2023
Contact:	Hilary Cosby, RN
Email:	hcosby1@jhmi.edu

Johns Hopkins clinical research office quality assurance group will monitor and audit this
study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal
monitoring at their site.

The Sub Investigator at each site will be responsible for internal monitoring at their site.
The site sub Investigator and study team will report any serious adverse events to Principal
Investigator and annually report adverse events.

Inclusion Criteria:

- Hereditary Pancreatitis or

- Peutz-Jeghers Syndrome or

- Strong family history of pancreas cancer on one side of the family tree or

- Confirmed germline mutation carrier (BRCA2, FAMMM, PALB2, BRCA1, HNPCC, PRSS1/2, or
CTRC

- Endoscopic evaluation of pancreas scheduled

Exclusion Criteria:

- Medical comorbidities or coagulopathy that contraindicate endoscopy

- Prior surgery that prevent optimal endoscopic ultrasound such as partial or complete
gastrectomy with Bilroth or Roux-en-Y anastomosis

- Stricture or obstruction in the upper GI tract that does not allow passage of the
echoendoscope

- Poor performance status

- Inability to provide informed consent

- Pregnancy.

We found this trial at

sites

Johns Hopkins Hospital

1800 Orleans St.
Baltimore, Maryland 21287

410-955-5000