Cervical Spinal Cord Metabolism and Microstructure in Amyotrophic Lateral Sclerosis(ALS)



Status:Terminated
Conditions:Neurology, Neurology, Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 80
Updated:6/6/2018
Start Date:October 2013
End Date:August 2015

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The investigators want to know if magnetic resonance imaging can accurately provide an early
diagnosis of amyotrophic lateral sclerosis (ALS).

Currently there is no definitive diagnostic test for amyotrophic lateral sclerosis (ALS). The
investigators' goal is to determine if magnetic resonance imaging can provide an accurate
diagnosis of ALS by looking at chemical concentrations in the spinal cord at the neck level
which show up in MRI imaging and compare these chemical concentrations to corresponding
measures in healthy control subjects.

Inclusion Criteria:

1. Adults age 18 to 80 years of age.

Exclusion Criteria:

1. Do not have active substance abuse

2. Do not have co-morbid psychiatric disease

3. Do not have opportunistic central nervous system infection

4. Do not have cerebrovascular disease

5. Do not have a contraindication for magnetic resonance imaging(MRI)(e.g. cardiac
pacemaker, ferromagnetic or metallic implants).

6. Are not pregnant

7. Have not had cervical spinal surgery(neck) -
We found this trial at
1
site
Ann Arbor, Michigan 48109
Principal Investigator: Bradley Foerster, M.D.
Phone: 734-615-3586
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mi
from
Ann Arbor, MI
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