High Fructose Corn Syrup
| Status: | Recruiting |
|---|---|
| Conditions: | Obesity Weight Loss, Gastrointestinal, Gastrointestinal |
| Therapuetic Areas: | Endocrinology, Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 4/2/2016 |
| Start Date: | March 2012 |
| End Date: | June 2016 |
| Contact: | Lynda Bowers, MSEd |
| Email: | lbowers@dom.wustl.edu |
| Phone: | 314-362-0590 |
The Effect of High Fructose Corn Syrup Feeding in Nonalcoholic Fatty Liver Disease
The purpose of this research study is to learn more about high fructose corn syrup, a sugar
used to sweeten drinks and foods, affects metabolism in obese persons with and without
nonalcoholic fatty liver disease. Eligible participants will be studied before and after
eating a diet high in high fructose corn syrup or a a standard diet (low in high fructose
corn syrup) for four weeks.
used to sweeten drinks and foods, affects metabolism in obese persons with and without
nonalcoholic fatty liver disease. Eligible participants will be studied before and after
eating a diet high in high fructose corn syrup or a a standard diet (low in high fructose
corn syrup) for four weeks.
Inclusion Criteria:
- IHTG >10% or <5%
- BMI 30.0-45.0 kg/m2
- Sedentary
- Consume <10% calories from high fructose corn syrup
- Weight stable for previous 3 months
Exclusion Criteria:
- IHTG 5.1-9.9%
- Children
- Adults over 65 years
- Pregnant
- Lactating
- Exercise >1.5 hours/week
- Hepatitis B or C
- Diabetes
- History of liver disease
- History of alcohol abuse
- Severe hypertriglyceridemia (>300 mg/dl)
- Smokers
- Anemia (Hemoglobin <10mg/dl)
- Not weight stable
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