The Effect of Immediate Implant Placement and Provisionalization in the Esthetic Zone

To qualify, patients must be between 18 to 79 years old, in good health, have a tooth in the
upper jaw (except molars) that needs to be extracted, and able and willing to return to the
University of Michigan Dental School for all follow-up appointments (8 follow-up visits over
a period of 12 months). Sufficient number of natural teeth and/or replacements to provide a
stable occlusion as determined by the investigator

Patients will be excluded for any of the following conditions: Women who are pregnant or
plan to become pregnant, an existing implant adjacent to the area of study, current smoker
or quit smoking less than one year ago, antibiotic therapy for more than two weeks within 3
months of baseline, need for antibiotics prior to dental treatment (due to prosthetic joint
replacement or other medical condition), chronic use of medications known to affect the gum
tissues (calcium channel blocker (less than 6 months, or over 6 months and have experienced
overgrowth of your gums), anticonvulsants, immunosuppressive drugs, nonsteroidal
anti-inflammatory medications...), current orthodontic treatment, or active periodontal
treatment. Participants must inform the investigators if they are enrolled in any other
studies because it may becloud them from participation in this study.

Inclusion Criteria:

- between 18 to 79 years old

- in good health

- have a single tooth in the upper jaw (except molars) that needs to be extracted

- able and willing to return to the University of Michigan Dental School for all
follow-up appointments (8 follow-up visits over a period of 12 months)

- Sufficient number of natural teeth and/or replacements to provide a stable occlusion
as determined by the investigator

Exclusion Criteria:

- an existing implant adjacent to the area of study

- current smoker or quit smoking less than one year ago

- antibiotic therapy for more than two weeks within 3 months of baseline, need for
antibiotics prior to dental treatment (due to prosthetic joint replacement or other
medical condition)

- chronic use of medications known to affect the gum tissues (calcium channel blocker
(less than 6 months, or over 6 months and have experienced overgrowth of your gums),
anticonvulsants, immunosuppressive drugs, nonsteroidal anti-inflammatory
medications...)

- current orthodontic treatment, or active periodontal treatment

- Women who are pregnant or plan to become pregnant during the course of the study, and
nursing mothers

- unstable medical condition or if you are unable to have routine dental surgery then
you should not participate in this study. If you are already participating in another
study, we ask that you inform the investigators because participating in more than
one study may be harmful to you.