Genetic Polymorphisms & The Risk for Sepsis After Trauma
| Status: | Recruiting |
|---|---|
| Conditions: | Hospital, Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | June 2013 |
| End Date: | December 2016 |
| Contact: | Laura Hennessy, RN |
| Email: | hennessy@uw.edu |
| Phone: | 206-744-7723 |
The specific aim of this is to establish a cohort of severely injured patients admitted to
our trauma center. Investigators will collect DNA, utilizing discarded blood samples, from
3000 injury victims in an effort to identify perhaps 50 - 100 single-nucleotide
polymorphisms (SNP) (out of 1000s) that can be used, when taken together, to identify
patients at highest risk for developing complicated sepsis and death.
our trauma center. Investigators will collect DNA, utilizing discarded blood samples, from
3000 injury victims in an effort to identify perhaps 50 - 100 single-nucleotide
polymorphisms (SNP) (out of 1000s) that can be used, when taken together, to identify
patients at highest risk for developing complicated sepsis and death.
Inclusion Criteria:
Admitted to the Intensive Care Unit (ICU) at Harborview Medical Center after suffering a
traumatic injury
- Have a sample of discarded blood that was obtained prior to any allogenic blood
transfusions
- Expected to be in the ICU for more than 24 hours
Exclusion Criteria:
- We will exclude subjects with chronic medical conditions for the reasons stated above
as well as vulnerable populations (children, pregnant females, and prisoners)
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