Stress Management Intervention for Mothers of Children With Cancer
Status: | Completed |
---|---|
Conditions: | Depression, Depression |
Therapuetic Areas: | Psychiatry / Psychology |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 7/11/2015 |
Start Date: | September 2010 |
End Date: | June 2014 |
Stress Management Intervention for At-Risk Mothers of Children With Cancer
To explore maternal biological (activation of the hypothalamic-pituitary-adrenal axis) and
behavioral (smoking, sleep behavior, exercise and alcohol use) pathways of
intervention-related decreases in inflammation. Hypothesis: The intervention group will show
decreased levels of cortisol and improved health behaviors from pre- to post-intervention
when compared with the control group. We will also explore whether intervention-related
changes in these parameters predict symptoms of illness. Exploratory Aim 2. To explore
psychological pathways of intervention-related decreases in distress among mothers,
including the perception of social support and the use of behavioral coping strategies that
are components of the intervention. Hypothesis: Increases in perceived social support and
use of active behavioral coping strategies will be associated with intervention-related
decreases in symptoms of depression, anxiety and psychological stress.
behavioral (smoking, sleep behavior, exercise and alcohol use) pathways of
intervention-related decreases in inflammation. Hypothesis: The intervention group will show
decreased levels of cortisol and improved health behaviors from pre- to post-intervention
when compared with the control group. We will also explore whether intervention-related
changes in these parameters predict symptoms of illness. Exploratory Aim 2. To explore
psychological pathways of intervention-related decreases in distress among mothers,
including the perception of social support and the use of behavioral coping strategies that
are components of the intervention. Hypothesis: Increases in perceived social support and
use of active behavioral coping strategies will be associated with intervention-related
decreases in symptoms of depression, anxiety and psychological stress.
Inclusion Criteria:
- biologic, adoptive, or legal guardian mothers of children (birth to 17 years) who
are within 6 weeks of being newly diagnosed with any cancer, with the exception of a
central nervous system (CNS) cancer or early stage lymphoma, recruited from the
Division of Hematology and Oncology, Children's Hospital of Pittsburgh (CHP)
- no reported clinical history of psychotic or bipolar illness, neurological disorder
(stroke, transient ischemic attacks, Parkinson's disease, multiple sclerosis) or
chronic disease known to influence immune function, including cardiovascular disease,
cancer [within the past 2 years], or autoimmune disease
- not taking medications that might alter responses to questionnaires or indices of
immune function (including major sedatives or glucocorticoid, anti-inflammatory,
anti-retroviral, or immunosuppressant medication)
- fluency in English (i.e., have commonly used English in everyday speaking and reading
for at least 10 years)
- is at least 18 years of age
- not working nightshifts exclusively.
Exclusion Criteria:
- mothers of children with CNS cancers due to our belief that a psychosocial
intervention tailored more specifically to the unique stressors inherent in this
diagnosis is warranted
- mothers of children with early stage lymphomas will be excluded because of their
child's brief/mild treatment course
- mothers whose child is older than 17 years will not be eligible; the upper age limit
(17 years) was established based on referral patterns at the CHP hematology/oncology
department.
We found this trial at
1
site
4401 Penn Avenue
Pittsburgh, Pennsylvania 15224
Pittsburgh, Pennsylvania 15224
412-692-5325
Children's Hospital of Pittsburgh of UPMC UPMC is one of the leading nonprofit health systems...
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